Research shows that expert-crafted worked examples can have a positive effect on student performance. To investigate the potential for data-driven worked examples to achieve similar results, we generated worked examples for the Deep Thought logic tutor, and conducted an experiment to assess their impact on performance. Students who received data-driven worked examples were much more likely to c...

We consider two popular, permutation-based, step-down procedures of p-values adjustment in multiple testing problems known as min P and max T and intended for strong control of the family-wise error rate, under the so-called subset pivotality property (SPP). We examine key but subtle issues involved in ascertaining validity of these methods, and also introduce a new, slightly narrower notion of...

Lower limb skin grafts are thought to have higher failure rates than skin grafts in other sites of the body. Currently, there is a paucity of literature on specific factors associated with lower limb skin graft failure. We present a series of 70 lower limb skin grafts in 50 patients with outcomes at 6 weeks. One-third of lower limb skin grafts went on to fail with increased BMI, peripheral vasc...

We have augmented the Deep Thought logic tutor with a Hint Factory that generates data-driven, context-specific hints for an existing computer aided instructional tool. We investigate the impact of the Hint Factory’s automatically generated hints on educational outcomes in a switching replications experiment that shows that hints help students persist in a deductive logic proofs tutor. Three in...

Objective: Nurse practitioner (NP) students at our graduate school of nursing use WISE-MDTM simulation modules in the curriculum. This prospective randomized controlled pilot study was undertaken to evaluate critical-thinking outcomes associated with adding metacognitive deliberate-reflection guidance to the learning strategy with WISE-MD simulation modules. Methods: Of 33 NP students randomly ...

We present a unifying approach to multiple testing procedures for sequential (or streaming) data by giving sufficient conditions for a sequential multiple testing procedure to control the familywise error rate (FWER). Together we call these conditions a "rejection principle for sequential tests," which we then apply to some existing sequential multiple testing procedures to give simplified unde...

Detection of positive Darwinian selection has become ever more important with the rapid growth of genomic data sets. Recent branch-site models of codon substitution account for variation of selective pressure over branches on the tree and across sites in the sequence and provide a means to detect short episodes of molecular adaptation affecting just a few sites. In likelihood ratio tests based ...