BACKGROUND A number of large trials have confirmed the benefits of thrombolysis in acute stroke, but there are gender differences. We sought to examine the relationship between sex and outcome after thrombolysis. METHODS This was a prospective cohort study including 1,272 incident ischemic strokes (597 in women) from April 1, 2006 to December 31, 2014. Statistical approaches were used for ana...

conclusions: the results obtained from this study support the idea that the timi and modified timi risk scores might be valuable tools that could be used to stratify the risk of patients with atypical chest pain in the emergency department. results: no significant difference could be observed between both groups regarding demographic characteristics, ejection fraction, left ventricle hypertroph...

Pulmonary embolism is a life-threatening condition treated with anticoagulation and systemic thrombolysis when appropriate. In patients with contraindications to thrombolysis, catheter-directed thrombolysis may be considered. Here, we present a patient with massive pulmonary embolus and 3 contraindications to systemic thrombolysis who was successfully treated with pharmacomechanical thrombolysi...

Background: At present, the treatment of acute ischaemic stroke (AIS) by aticepase (rt-PA) in emergency veins has become main mode hospital, but research on early hemorrhage complications patients with thrombolysis is rarely reported. This aims to study earlier warning index thrombolysis.

Background The Society of Vascular & Interventional Neurology Guidelines and Practice Standards committee established the “Brief Update” format to provide up‐to‐date recommendations on focused clinical topics with emerging trial results. For our inaugural Brief Update, we review current evidence for administering intravenous thrombolysis before mechanical thrombectomy; combination therapy (...

Laser-enhanced thrombolysis by high intensity focused ultrasound (HIFU) treatment was studied in vitro with bovine blood clots. To achieve laser-enhanced thrombolysis, laser light was employed to illuminate the sample concurrently with HIFU radiation, and ultrasound and laser parameters were optimized to achieve better thrombolysis efficiency. The results indicated that the thrombolysis efficie...

BACKGROUND Coronary artery bypass grafting (CABG) is frequently used after thrombolytic therapy. However, there is little information regarding long-term survival in this setting. The purpose of the present study was to compare the long-term survival of patients subjected to CABG after thrombolysis to those without thrombolysis. METHODS AND RESULTS We studied 3760 consecutive patients with is...

BACKGROUND Current guidelines recommend that patients with acute myocardial infarction should receive thrombolysis within 60 min of seeking professional help. AIM To compare current rates of pre-hospital thrombolysis in Grampian with historical data, and assess the effect of pre-hospital thrombolysis on the proportion of patients achieving 'call-to-needle' times within national guidelines. ...

BACKGROUND AND AIM High-risk pulmonary embolism (PE) represents an important health problem in emergency cardiology, being associated with a high rate of mortality. The aim of this study is to assess the efficacy and safety of pulmonary intra-arterial thrombolysis with streptokinase compared to systemic thrombolysis. METHODS AND RESULTS In our study, 28 patients with acute high risk PE were t...

BACKGROUND Although thrombolysis is considered to be the first-line treatment for ischemic stroke, there remains an ongoing controversy on the safety and efficacy of thrombolysis in cervical artery dissection (CAD). The aim of this meta-analysis was to assess observational data related to the safety and efficacy of thrombolysis in CAD-related ischemic stroke. METHODS We performed a systematic...