factor v leiden deficiency is the most common hereditary hypercoagulable disease in the united states and involves 5% of the caucasian population. up to 30% of patients who present with deep vein thrombosis (dvt) or pulmonary thromboembolism present with this condition. this is a case report of a 36-year-old man who experienced one episode of dvt within the previous year and was admitted to our...

background: the objective of this study is to optimize the effective dose of heparin and ligustrazine hydrochloride injection (lhi) for drug combination. materials and methods: the animal clinical study of lhi was performed by the rat’s model of induced arteriovenous shunt thrombosis. experimental animals were grouped into several groups and separately treated with both lhi (20, 40, 80 mg/kg, i...

the presence of tumor thrombus in the right atrium is frequently the result of direct intraluminal extension of infra-diaphragmatic malignancy into the inferior vena cava (ivc) or supradiaphragmatic carcinoma into the superior vena cava (svc). right atrial tumor thrombus with extension into both svc and ivc has not been reported in the literature. we present a patient who presented with symptom...

International travel has become increasingly common and accessible, hence, about two billion passengers undertake international and domestic air travel each year. Venous thromboembolism (VTE) is a serious public health disorder which may occur following prolonged travel, especially after air travel. A direct relation between VTE development and prolonged travels has been documented, while some ...

Introduction: It is well known that the tendency toward thrombosis is increased in cancer patients. The increase in cancer procoagulant and tissue factor levels, endothelial damage, and stasis due to compression are among the most accused causes of thrombosis in cancer patients. Hypereosinophilia is a rare condition that causes endothelial damage leading to thrombosis. <s...

background: pulmonary embolism (pe) is the most life-threatening form of venous thrombosis which causes the majority of mortalities in this category. obstructive sleep apnea (osa) has been indicated as one of the risk factors for thromboembolism because of hemostatic alterations. the present study was designed to seek for the relationship between osa and 30-day mortality of patients with pe. ma...

PURPOSE To evaluate in-vivo thrombus compressibility in abdominal aortic aneurysms (AAAs) to hopefully shed light on the biomechanical importance of intraluminal thrombus. METHODS Dynamic electrocardiographically-gated computed tomographic angiography was performed in 17 AAA patients (15 men; mean age 73 years, range 69-76): 11 scheduled for surgical repair and 6 under routine surveillance. T...

BACKGROUND Left atrial appendage (LAA) thrombus is an accepted risk factor for ischemic stroke. Following a literature review we were unable to identify a study that determined the incidence of ischemic stroke in patients with a confirmed LAA thrombus. The purpose of this study was to establish the incidence of ischemic stroke in patients with a LAA thrombus confirmed on trans-oesophageal echoc...