For intensities of the PHELIX laser [1] the Target Normal Sheath Acceleration (TNSA) is the most important acceleration mechanism. The ion beams accelerated in this way should be collimated and transported by a solenoid to other accelerator components. In order to optimize the transport and to increase the collimation dedicated simulation studies are needed [1]. The two dimensional phasespace d...

CO2 laser-plasma interactions provide a unique parameter space for using a gas jet for Target Normal Sheath Acceleration (TNSA) of ions instead of a thin foil target. The generation of 1-5 MeV protons from the interaction of a 3 ps TW CO2 laser pulse with a gas target with a peak density around the critical plasma density (10 cm) has been studied by 2D particle-in-cell simulations. The proton a...

Over the last several years, the Target Normal Sheath Acceleration (TNSA) mechanism in solid density plasmas produced by a laser pulse has achieved proton energies up to 10’s of MeV and quasi-monoenergetic beams at lower energies. Although solid-target experiments have demonstrated high-charge and low-emittance proton beams, little work has been done with gaseous targets which in principle can ...

The excision of transposon Tn7 from a donor site and its insertion into its preferred target site, attachment site attTn7, is mediated by four Tn7-encoded transposition proteins: TnsA, TnsB, TnsC, and TnsD. Transposition requires the assembly of a nucleoprotein complex containing all four Tns proteins and the DNA substrates, the donor site containing Tn7, and the preferred target site attTn7. T...

Laser-ion acceleration has been of particular interest over the last decade for fundamental as well as applied sciences. Remarkable progress has been made in realizing laser-driven accelerators that are cheap and very compact compared with conventional rf-accelerators. Proton and ion beams have been produced with particle energies of up to 50MeV and several MeV/u, respectively, with outstanding...

The bacterial transposon Tn7 is capable of high-frequency transposition to a specific site in the Escherichia coli chromosome, attTn7, and of low-frequency transposition to sites other than attTn7. Using an in vitro insertional mutagenesis procedure, we have identified and characterized five tns (Tn seven) genes that are essential for Tn7 transposition. Three of these genes, tnsA, tnsB, and tns...

Abstract Bacterial transposons propagate through either non-replicative (cut-and-paste) or replicative (copy-and-paste) pathways, depending on how the mobile element is excised from its donor source. In well-characterized E. coli transposon Tn 7 , a heteromeric TnsA-TnsB transposase directs cut-and-paste transposition by cleaving both strands at each end during excision step. Whether similar pa...