background in the golestan cohort study that was launched to investigate the causes of esophageal cancer, a complete biospecimen bank was established for storage of collected blood, urine, hair, and nail samples. the objective of this study was to evaluate the feasibility of nail samples as a biomarker of selected trace elements status. methods thirty toenail samples were selected randomly from...

only two facts on which all are agreed. The first is, that the complaint is caused by the wearing of tight boots; the second, that it is not ingrowing of the toe-nail at all, but overgrowing of the toe-flesh. With reference to the first point, it seems to have struck no one as peculiar that the leaving off tight boots is by no means a cure for the malady. Sublata causa, tollitxir effectus ought...

Subungual pigmentation may have a variety of underlying pathologies, but clinicians should consider malignancies such as subungual melanoma or metastasis, even if they are not common. A delayed diagnosis can dramatically worsen the prognosis. Therefore, histologic examination is highly recommended. We present a 75-year-old female cancer patient presenting with subungual blackish pigmentation of...

Fungal organisms could be present in the nail without any clinical manifestations. As onychomycosis in diabetics has more serious complications, early detection of such infection could be helpful to prevent them. We aim in this study to assess the possibility of detecting subclinical onychomycosis in type II diabetic patients and addressing possible associated neuropathy. A cross sectional, obs...

Sib,?A very simple and painless way of removing an ingrowing toe-nail is by the application of lunar caustic, but as it does not appear to be generally known, I shall here describe it for the benefit of the profession. A solid piece of lunar caustic should he well applied daily over the whole of the affected nail, which, in a few days, wiil become sufficiently detached, so as to allow of its be...

onychomycosis constitutes the most common fungal infection of nail affecting finger and toe nails as well. antifungals found to be effective in the treatment of onychomycosis. however, transport of oral antifungal agents exhibits more toxicity and requires longer treatment period. medicated nail lacquers proved to cause lesser toxicity and required shorter treatment period. it provides not only...

"Nailing" the management of the severely ingrown great toenail, commonly encountered in the adolescent population, is an important tool in the pediatrician's armamentarium. I have found great toenail removal to be worthwhile, with straightforward indications; and quite rewarding for my patients in terms of time, convenience, and costs. The key to the procedure is to keep it simple. Four basic v...

Onychomycosis constitutes the most common fungal infection of nail affecting finger and toe nails as well. Antifungals found to be effective in the treatment of onychomycosis. However, transport of oral antifungal agents exhibits more toxicity and requires longer treatment period. Medicated nail lacquers proved to cause lesser toxicity and required shorter treatment period. It provides not only...

Jennifer Trainor, MD, pediatric emergency room physician: The fancy name is onychocryptosis. There are several degrees of involvement ranging from minimal erythema and edema to a large, swollen toe with purulent drainage. The etiology is felt to relate to improper growth of the nail penetrating the skin. This may be due to improper nail trimming, which leaves a curved, sharp nail or to an unusu...