OBJECTIVES Oral tongue cancer may have a distinct epidemiological profile from other mucosal neoplasms of the oral cavity. We sought to further define the demographic characteristics associated with oral tongue cancer to determine if unique characteristics exist compared with other oral cavity cancers. STUDY DESIGN Cross-sectional analysis using cross-tabulations and multivariate regression m...

BACKGROUND Tongue cancer is still a major health problem in most developing countries around the world. Statistics shown the number of tongue cancers, especially in early age, to be increasing, with poor survival. OBJECTIVE To analyze the characteristic profile of tongue cancer patients in Indonesia as well as the survival rate. MATERIALS AND METHODS A cross sectional study was conducted in...

The physical status of humans can be estimated by observing the appearance of the tongue coating, known as tongue diagnosis. The goals of this study were to reveal the relationship between tongue coating appearance and the oral microbiota in patients with gastric cancer and to open a novel research direction supporting tongue diagnosis. We used a tongue manifestation acquisition instrument to a...

introduction: as one of the most common cancers among head and neck malignancies, cancer of the oral cavity probably has some variations in countries with a high prevalence of esophageal cancer.  materials and methods: patients with oral cavity cancer who were treated at two tertiary referral centers from january 1999 to january 2009 were included in this study. in addition to demographic data,...

Introduction Presence of two primary malignancies is rare and occurs in 3-5% of the cancer patients. As per our extensive internet research, this is the only reported case of a synchronous sino-nasal embryonal rhabdomyosarcoma with squamous cell carcinoma-tongue. The case report is important because of the rare diagnosis and the challenge we faced in the diagnosis and treatment of the pat...

EZH2, a core member of the Polycomb Repressor Complex 2 (PRC2), mediates transcriptional silencing by catalyzing the trimethylation of histone 3 lysine 27 (H3K27), which plays key roles in cancer initiation and progression. Here, we investigated the expression pattern and biological roles of EZH2 in tongue tumorigenesis by loss-of-function assays using small interference RNA and EZH2 inhibitor ...

OBJECTIVES Tongue is the most important phonatory organ in stomatognathic system. Radical resection of tongue squamous cell carcinoma can cause tongue defect and result in serious oral dysfunction, especially in phonetic function. This study aims to reveal the influence of tongue cancer, tongue defect and tongue reconstructions to phonetic function of tongue cancer patients. STUDY DESIGN Form...

introduction: the clinical outcome of patients with squamous cell carcinoma (scc) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. interleukin-6(il-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. the aim of this study was to investigate the serum le...

We investigated whether neck dissection should be performed to prevent T1-2N0M0 tongue cancer by using the Weiss and colleague's decision tree method. The results showed that preventive neck dissection should not be recommended for T1-2N0M0 tongue cancer. However, preventive neck dissection is a suitable approach when treating tongue cancer tumors with a thickness of ≥ 4 mm.

background: since the earliest days of medicine, the tongue has been considered a good reflection of systemic disease. hip­pocrates, galen and others considered the tongue to be barometer of health. in addition, the early diagnose of tongue le­sions help to recognize the some systemic diseases. the purpose of this study was to determine the frequency of different mor­phological variations (anom...