BACKGROUND To describe the first reported case of toxic optic neuropathy secondary to docetaxel (Taxotere®) chemotherapy. CASE PRESENTATION A 53-year-old female presented with predominantly unilateral visual loss, but extensive bilateral visual field defects and bilateral optic nerve head swelling 2 weeks after first dose of docetaxel (Taxotere®) and trastuzumab (Herceptin®) chemotherapy for ...

conclusions demyelinating disease, anterior ischemic optic neuropathy, non-arteritic anterior ischemic optic neuropathy, autoimmune disease, and hereditary optic neuropathy could cause optic neuropathy. normal cbc parameters and the absence of clinical manifestations of vitamin b12 deficiency could not rule out its diagnosis. careful physical examinations and history-taking with a classical app...

Optic neuropathy is a frequent cause of vision loss encountered by ophthalmologist. The diagnosis is made on clinical grounds. The history often points to the possible etiology of the optic neuropathy. A rapid onset is typical of demyelinating, inflammatory, ischemic and traumatic causes. A gradual course points to compressive, toxic/nutritional and hereditary causes. The classic clinical signs...

The causes of nonglaucomatous optic disk atrophy and excavation are enumerated in people 65 years or older: congenital anomalies, myopia, ischemic disorders, transsynaptic degeneration, traumatic, compressive, hereditary, toxic and infectious optic neuropathy.

OBJECTIVE To refine the criteria for the diagnosis of amiodarone-related optic neuropathy by including a broader spectrum of clinical features, thus helping to differentiate this entity from nonarteritic anterior ischemic optic neuropathy coincidentally affecting a patient taking amiodarone. METHODS A retrospective case review of 22 patients who developed optic neuropathy while taking amiodar...

PURPOSE To present a unilateral central visual field defect in a patient with psoriatic arthritis treated with Methotrexate and folic acid supplement, probably induced by toxic posterior optic neuropathy. The scotoma incompletely resolved after cessation of Methotrexate (MTX) therapy. METHODS Serial fundoscopic, perimetric and electrophysiological examination as well as comprehensive neurolog...