نتایج جستجو برای: toxicogenetics

تعداد نتایج: 24  

2015
Lúcia Maria de Miranda Adad Heloísa Helena Rodrigues de Andrade Kátia Kvitko Mauricio Lehmann Ana Amélia de Carvalho Melo Cavalcante Rafael Rodrigues Dihl

Farm workers are often exposed to pesticides, which are products belonging to a specific chemical group that affects the health of agricultural workers and is mostly recognized as genotoxic and carcinogenic. The exposure of workers from Piauí, Brazil, to these hazardous chemicals was assessed and cytogenetic alterations were evaluated using the buccal micronucleus assay, hematological and lipid...

Journal: :Pharmacogenomics 2010
Ivan Rusyn Daniel M Gatti Timothy Wiltshire Steven R Kleeberger David W Threadgill

The rapid decline in the cost of dense genotyping is paving the way for new DNA sequence-based laboratory tests to move quickly into clinical practice, and to ultimately help realize the promise of 'personalized' therapies. These advances are based on the growing appreciation of genetics as an important dimension in science and the practice of investigative pharmacology and toxicology. On the c...

2014
Gelareh Alam Byron C. Jones

Heavy metals, various pesticide and herbicides are implicated as risk factors for human health. Paraquat, maneb, and rotenone, carbamate, and organophosphorous insecticides are examples of toxicants for which acute and chronic exposure are associated with multiple neurological disorders including Parkinson's disease. Nevertheless, the role of pesticide exposure in neurodegenerative diseases is ...

Journal: :asia pacific journal of medical toxicology 0
sohini das biswas post graduate department of conservation biology, durgapur government college, durgapur, india babli garai post graduate department of conservation biology, durgapur government college, durgapur, india moitreyee banerjee department of zoology, durgapur government college, durgapur, india

background: tobacco use has toxic effects on different organs. this study was carried out to assess the effect of indigenous tobacco both in smoking (bidi) and smokeless (gutkha, zarda and khaini) forms on buccal cells at chromosomal level, through assessment of different nuclear anomalies as biomarker. methods:this study was done on people living in durgapur and its adjacent areas, west bengal...

Journal: :Journal of health sciences and medicine 2021

Aim: The aim of this study was to examine the most common studies about molecular biology and genetics related COVID-19. In addition, also determine subject focus COVID-19 during pandemic with data mining.
 Material Method: Review research articles, book chapters, conference abstracts, case reports mini reviews published between March 2020 July 2021 were included in study. We retrieved onl...

2012
Teresa C. Leal Alphonse Kelecom

Since the 19th century, with industrial and urban development and the consequent increase in emissions from industrial activities and vehicular emissions have been observed air pollution effects on living organisms. Thus, since the beginning of the twentieth century, have been carried out several studies that include studies of the effect of pollution on plants (Chies,1983). Some features obser...

2011
Peter W. Stacpoole

BACKGROUND Dichloroacetate (DCA) is known to environmental scientists as a by-product of water chlorination and as a metabolite of industrial solvents, including Superfund chemicals. In contrast, DCA is studied by clinical investigators for its therapeutic potential in several life-threatening conditions, including genetic mitochondrial diseases, pulmonary arterial hypertension, and cancer. Thu...

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