background: since the treatments of long tracheal leisions are associated with some limitations, tissue enginered trachea is considered as an alternative option. this study aimed at preparing a composite scaffold, based on natural and synthetic materials for tracheal tissue engineering. methods: nine chitosan silk-based scaffolds were fabricated using three freezing rates (0.5, 1, and 2°c/min) ...

conclusions: the potent effect of corticosteroids in the rapid improvement of respiratory compromise associated with thyroid lymphoma represents an important clinical finding. this opens the possibility for the favorable response to corticosteroid therapy to be regarded as a possible preliminary diagnostic tool for thyroid lymphoma in acute respiratory distress patients in the absence of trache...

the β2-adrenergic effects of macerated extract, aqueous extract, ethanol extract, and essential oil of carum copticum, 5 nm propranolol, and saline were tested by performing cumulative log concentration-response curves of isoprenaline-induced relaxation of precontracted isolated guinea pig tracheal chains in three different conditions including: non-incubated (group 1, n=9) incubated with 1 µm ...

in a previous study, the relaxant and anticholinergic (functional antagonism) effects of bunium persicum (b. persicum ) have been demonstrated on guinea pig tracheal chains. to elucidate the other mechanisms responsible for this relaxant effect, the inhibitory effect of this plant on histamine h1 receptors was examined in this study. the antihistaminic effects of aqueous and macerated extracts,...

Background The tracheal cartilage plays an important role in maintaining the mechanical stability of the trachea, as it keeps the trachea open and prevents its collapse under the negative pressures of the respiratory cycle. This study aimed to evaluate and compare the mechanical properties of cartilage specimens from the cranial and caudal regions of the human trachea and compare the results wi...

the exact role of the epithelial lining of the trachea in modulating the bronchial tone is controversial. the present study was an attempt to verify the role of both prostaglandins and mast cells in the acute phase of acid inspiration in rat. four groups (n = 6) of n. mari rats were employed. the first group was used as placebo control, and normal saline was injected. to the second group hydroc...

a 25 year-old construction worker underwent neck laceration following penetrating neck trauma in a falling incident. the 3rd tracheal ring was injured which was initially repaired and the patient was discharged in good general condition. (figure 1 shows the patient’s neck view after discharge from hospital).two months later the patient was again admitted due to provocative coughing and a metal ...

asthma  is a clinical syndrome  characterized by chronic  airway inflammation, airway responsiveness, and expiratory airflow limitation. nocturnal symptoms and decreases in lung function are common aspects of the asthma clinical syndrome. nocturnal symptoms also appear to be associated with asthma-related mortality. in addition to its importance to the regulation of human circadian rhythms, an ...

A case of adenoid cystic carcinoma located in trachea, primarily wrongly recognized as a thyroid cancer is presented with an update of the literature. The patient underwent surgical treatment (total thyroidectomy, and partial resection of trachea). Histopathological examination found trachea as a primary location of ACC and thyroid tumour as a metastatic one. After operation the patient underwe...