نتایج جستجو برای: tranexamic acid

تعداد نتایج: 747457  

Introduction:Bleeding is a common concern during functional endoscopic sinus surgery (FESS) that can increase the risk of damage to adjacent vital elements by reducing the surgeon’s field of view. This study aimed to explore the efficacy of topical tranexamic acid in reducing intraoperative bleeding. Materials and Methods:This double-blind, randomized clinical trial was conducted in 60 patients...

2012
Ian Roberts Pablo Perel David Prieto-Merino Haleema Shakur Tim Coats Beverley J Hunt Fiona Lecky Karim Brohi Keith Willett

OBJECTIVES To examine whether the effect of tranexamic acid on the risk of death and thrombotic events in patients with traumatic bleeding varies according to baseline risk of death. To assess the extent to which current protocols for treatment with tranexamic acid maximise benefits to patients. DESIGN Prespecified stratified analysis of data from an international multicentre randomised contr...

Journal: :nephro-urology monthly 0
pejman pourfakhr department of anesthesiology, tehran university of medical sciences, tehran, ir iran elham gatavi department of anesthesiology, tehran university of medical sciences, tehran, ir iran shahram gooran department of urology, tehran university of medical sciences, tehran, ir iran farhad etezadi department of anesthesiology, tehran university of medical sciences, tehran, ir iran mohamad reza khajavi department of anesthesiology, tehran university of medical sciences, tehran, ir iran reza pourroustaei department of anesthesiology, shahid beheshti university of medical sciences, tehran, ir iran

conclusions the present study showed that local administration of tra significantly reduces bleeding after prostatectomy surgery and is effective in preventing postoperative hemoglobin decrease. objectives in this study, the effect of local administration of tra on reducing bleeding during prostatectomy surgery was evaluated. methods a total of 186 patients who underwent prostatectomy surgery w...

صابری, هوشنگ, مجتبی میری, سید, پردل نامدار, منصور,

Background: Topically applied tranexamic acid has been shown to decrease the amount of blood loss associated with major spinal surgical procedures. The aim of this study was to evaluate the effects of locally applied tranexamic acid in epidural space on post-laminectomy blood loss. Methods: One hundred patients who were scheduled to undergo laminectomy in Imam Khomeini Hospital in T...

2017
Sergey Pisklakov Haitham Ibrahim

The beneficial role and efficacy of Tranexamic Acid in reducing perioperative blood loss and blood transfusion requirements in spine surgery is being established. Tranexamic Acid is an antifibrinolytic agent traditionally used to lessen perioperative blood loss. Tranexamic Acid can be administered orally, intramuscularly, intravenously or topically. Tranexamic Acid studies in spine surgery have...

2014
Stephen McGrath Piers Yates Gareth Prosser

Intravenous Tranexamic acid has been shown to decrease blood transfusion requirements in surgery. Little evidence exists regarding the much cheaper oral form. The objective of this cohort study was to evaluate whether oral tranexamic acid administration in patients undergoing elective hip and knee replacement surgery resulted in decreased transfusion requirements. Methods: We assessed the trans...

2016
Young-Jun Seol Jong-Keun Seon Seung-Hun Lee Cheng Jin Jatin Prakash Yong-Jin Park Eun-Kyoo Song

PURPOSE Total knee arthroplasty (TKA) accompanies the risk of bleeding and need for transfusion. There are several methods to reduce postoperative blood loss and blood transfusion. One such method is using tranexamic acid during TKA. The purpose of this study was to confirm whether tranexamic acid reduces postoperative blood loss and blood transfusion after TKA. MATERIALS AND METHODS A total ...

  Background: The most appropriate route of tranexamic acid administration is controversial. In the current study, we compared the efficacy of intravenous (IV) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. Methods: One hundred twenty 120 patients were scheduled to undergo primary total knee arth...

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2010
Dumbor L Ngaage John Martin Bland

In view of the safety concerns that led to the withdrawal of aprotinin, should antifibrinolytics be used indiscriminately in cardiac surgery? This meta-analysis examines the efficacy and safety profile of tranexamic acid, and in comparison to aprotinin. We identified randomised trials and large observational studies investigating the use tranexamic acid from January 1995 to January 2009 using P...

Journal: :American journal of perinatology 2014
Elizabeth M McClure Bonnie Jones Doris J Rouse Jennifer B Griffin Beena D Kamath-Rayne Allan Downs Robert L Goldenberg

OBJECTIVE Postpartum hemorrhage (PPH) is a major cause of maternal mortality, with almost 300,000 cases and ~72,000 PPH deaths annually in sub-Saharan Africa. Novel prevention methods practical in community settings are required. Tranexamic acid, a drug to reduce bleeding during surgical cases including postpartum bleeding, is potentially suitable for community settings. Thus, we sought to dete...

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