We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to dis...

We report a 61-year-old man with multiple colored skin papules with central crusts in an archiform and linear pattern on his forehead as well as verrucus and hyperkeratotic plaques with central perforation on hands. Histologic examination of the lesions demonstrated a narrow channel of epidermal perforation containing notrophils, basophilic debris and elastic fibers with eosinophilic degenerati...

Membranous lipodystrophy represents a peculiar type of fat necrosis that is present in patients with various types of skin disease. It is characterized by the presence of microcysts and macrocysts and is lined by amorphous eosinophilic material with a crenelated arabesque appearance. These findings have been associated with lupus erythematosus, diabetes mellitus, erythema nodosum, trauma, etc. ...

Histoid leprosy is extremely rare in children. Molluscum contagiosum-like lesions in the setting of histoid leprosy is a highly atypical presentation and may signify the process of "transepidermal elimination" in lesions with high bacillary load. A case of histoid leprosy with umbilicated papules and nodules mimicking molluscum contagiosum is reported in a 10-year-old Indian boy.

Pilomatricoma or benign calcifying epithelioma of Malherbe is a benign appendageal tumour originating from primitive cells of the hair matrix. Perforation (transepidermal elimination), bullous or anetodermic cutaneous changes overlying pilomatricomas are rare events. In this report, we describe a case of pilomatricoma with bullous appearance or secondary anetoderma. The tumour was totally excis...