b-cyclodextrin glucosyl transferase (b-cgtase) hydrolyses starch to produce b-cyclodextrin by transglycosylation (cyclization) activity. the conventional method for detection of b-cgtase activity is based on detecting starch hydrolysis by iodine staining. this method reveals all amylolytic enzymes, but can not discriminate them. in the present study, we introduce a new method for specific detec...

orchard workers in north china are highly exposed to orchard pollens, especially peach and other rosaceae family pollens during pollination season. the aim of this study was to investigate whether occupational allergy to peach tree pollen as a member of rosaceae family is ige-mediated and to evaluate the cross-reactivity among rosaceae family pollens. allergen skin test and conjunctival challen...

glutathione transferase (gst) is a family of multifunctional detoxification enzymes which are mainly cytosolic that detoxify natural and exogenous toxic compounds through conjugation with glutathione tripeptide. its conjugates can be transported to vacuoles or apoplast. these conjugates are generally less toxic than the parent compounds. glutathione transferase is identified and isolated from m...

background : progression of systemic lupus erythematosus (sle) could be due to oxidative stress especially through reactive oxygen species (ros). detoxification of ros is largely performed by glutathione s-transferases (gsts), therefore polymorphisms of gstm1, gstt1 and gstp1 genes which decrease enzymes activity could affect sle susceptibility. the aim of this study was to determine the effect...

background: glutathione s-transferases ( gsts ) have been investigated as potential carcinoma susceptible genes. however, the relationship between gsts ( gstm1 , gstt1 ) variants and gastric carcinoma (gc) risk has been controversial in chinese population. methods: a comprehensive literature search strategy (pubmed, chinese biomedical database, chinese national knowledge infrastructure, wan fan...

objective(s):to the best of our knowledge, this is the first report on the contributions of gst genetic variants to the risk of diabetic retinopathy in an iranian population. therefore, the objective of this study was to determine whether sequence variation in glutathione s-transferase gene (gstm1 and gstt1) is associated with development of diabetic retinopathy in type 2 diabetes mellitus (t2d...

background cellular level of enzyme activity can serve as a reliable biomarker in the event of environmental/chemical insults. objectives the present study investigated time-dependent alterations of erythrocyte glutathione s-transferase (ery-gst) activity of non-malarious guinea pigs (cavia tschudii) administered with pyrimethamine/sulfadoxine and artemether/lumefantrine combination therapies. ...

background: urinary oxalate and citrate are the keyfactors in caox urolithiasis of cats and gamma glutamyltransferase is a good test for assessment of kidney damage.favorable effects of cynodon dactylon on calcium oxalate stoneformation have recently been proved in rats. objectives: thepresent study was designed to investigate the alteration ofurinary oxalate, citrate, and ggt after administrat...

background the molecular mechanism of hepatitis c-virus (hcv) genome-specific pathogenesis remains unclear. oxidative stress is an important pathophysiological mechanism in chronic hcv infection, but its relation to hcv genotypes has not been thoroughly examined. objectives in the present case-control study, the effect of diverse hcv genotypes on oxidative status changes was investigated. patie...

the aim of this study was to assess the possible association between genetic polymorphisms of the glutathione s-transferase (gst) gene family and the risk of the development of metabolic syndrome (ms) in zoroastrian females in yazd, iran.in this case-control study, gstm1, t1, and p1 polymorphisms were genotyped in 51 randomly selected ms patients and 50 randomly selected healthy controls on feb...