OBJECTIVE To assess the 30-day and 1-year mortality associated to the red blood cell transfusion after coronary artery bypass grafting surgery. This procedure has been questioned by the international medical community, but it is still widely used in cardiac surgery. Therefore, it is needed more evidence of this medical practice in our country. METHODS We retrospectively analyzed 3,004 patient...

OBJECTIVE The storage time of allogeneic red blood cells (RBCs) has been linked with the risk of severe postoperative infections following cardiac surgery. However, existing data are sparse and inconsistent. We therefore examined the association between the age of transfused RBCs and development of severe postoperative infection following coronary artery bypass grafting (CABG) in a large popula...

life-long red blood transfusion remains the main treatment for severe thalassemia. the development of hemolytic alloantibodies and erythrocyte autoantibodies complicated transfusion therapy in thalassemia patients. the frequency causes and prevention of this phenomenon among 80 transfused thalassemia patients were evaluated in ali asghar children's hospital during 1998-2004 in a cross-sectional...

Thirty frequently transfused patients on long term hemodialysis were studied and a similar number of age and sex-matched patients who were infrequently transfused were used as a control group to ascertain the influence of a previous myocardial infarction (MI) on transfusion requirements. The frequency of previous MI on electrocardiogram (ECG) in the transfused and control groups was similar (40...

Background Massive transfusion protocols (MTPs) are associated with severe hypocalcemia, contributing to coagulopathy and mortality in severely injured patients. Severity of hypocalcemia following massive activation appropriate treatment strategies remain undefined. Study design methods This was a retrospective study all MTP activations adult trauma patients at Level 1 center between August 201...

the purpose of this study has been to evaluate various factors influencing prognosis in children with hemolytic-uremic syndrome (hus). forty children with classical picture of hus were seen in 1986-1 991. boys and girls were equally affected, aged from two months to ten years. in 35 patients (87.5%) there was a history of diarrhea which was bloody in25. all were treated with peritoneal dialysis...

A specific enzyme immunoassay (EIA) for the diagnosis of hepatitis C virus (HCV) infection was developed by recombinant DNA technology. Abbott HCV EIA was used to detect antibody to HCV (anti-HCV) in non-transfused and multiply-transfused thalassemia patients. None of 11 non-transfused patients had anti-HCV but 3 of 52 (5.8%) multiply-transfused patients had anti-HCV. This study showed that the...

hepatitis c virus (hcv) infection is highly prevalent in thalassemic patients, and this may decrease the serum antibody response to hepatitis b virus (hbv) vaccine. there is also some alteration of the immune system in multi-transfused thalassemic patients, as a consequence of iron overload. we investigated whether hcy infection may reduce the effectiveness of hby vaccine in multi - transfused ...