b a ckground: the aim of the study was to evaluate and compare the efficiency and practicality of seven trappingmethods for adult phlebotominae sand flies. the results of this investigation provide information to determine the species composition and nocturnal activity pattern of different sand fly species. m e t hods: the study was carried out in both plain region (about 5km far from northeast...

eucalyptus species are cultivated in homogeneous plantations in brazil, mainly to supply woodfor the cellulose and steel industries, which favors the establishment of insect pests. the objective was todetermine the geographical distribution and structure abundance of lepidoptera defoliators of eucalypt.primary pest species of eucalypt of the order lepidoptera were found in all areas sampled and...

Neutrophil extracellular traps (NETs) have been implicated in the development of certain immune-mediated diseases, but their role in psoriasis has not been clearly defined. Human β-defensin-2 (HBD-2) is an important antimicrobial peptide overexpressed in psoriasis epidermis. We evaluated whether the amount of NETs is increased in psoriasis and determined the effect of NETs on HBD-2 production i...

Neutrophil extracellular traps (NETs) are made of processed chromatin bound to granular and selected cytoplasmic proteins. NETs are released by white blood cells called neutrophils, maybe as a last resort, to control microbial infections. This release of chromatin is the result of a unique form of cell death, dubbed "NETosis." Here we review our understanding of how NETs are made, their functio...

Introduction A novel antimicrobial mechanism of neutrophils involves the release of neutrophil extracellular traps (NETs) into the local environment to bind pathogens. NETs are composed of chromatin, and it has been proposed that a source of autoantigens in Systemic Lupus Erythematosus (SLE) could be increased NETs production. Interferon (IFN)-a is known to be a key player in the pathogenesis o...

MOTIVATION Neutrophil extracellular traps (NETs) are believed to be essential in controlling several bacterial pathogens. Quantification of NETs in vitro is an important tool in studies aiming to clarify the biological and chemical factors contributing to NET production, stabilization and degradation. This estimation can be performed on the basis of fluorescent microscopy images using appropria...

Pattern recognition is an integral part of the innate immune system. The human contact system has been shown to interact with the surface of many bacterial and fungal pathogens, and once activated leads to the generation of antimicrobial peptides and the proinflammatory mediator bradykinin. Here we show that apart from these surfaces also neutrophil extracellular traps (NETs) provide a surface ...

Neutrophils have recently been shown to release DNA-based extracellular traps that contribute to microbicidal killing and have also been implicated in autoimmunity. The role of neutrophil extracellular trap (NET) formation in the host response to nonbacterial pathogens has received much less attention. Here, we show that the protozoan pathogen Toxoplasma gondii elicits the production of NETs fr...

Recent investigations have highlighted new roles for neutrophils in the biology of infection and inflammation. Neutrophils are one of the main players in the innate immune system and actively contribute to host defense by killing pathogens. Added to their ability to eliminate microorganisms by phagocytosis, neutrophils can also kill microbes by capturing them in extracellular structures consist...