In polytrauma patients a thoracic trauma is one of the most critical injuries and an important trigger of post-traumatic inflammation. About 50% of patients with thoracic trauma are additionally affected by bone fractures. The risk for fracture malunion is considerably increased in such patients, the pathomechanisms being poorly understood. Thoracic trauma causes regional alveolar hypoxia and, ...

background: hypoxemia is a frequent complication after general anesthesia. it usually takes longer to recover in individuals with respiratory problems. bakers may suffer from respiratory problems such as asthma. the objective of this study was to compare the occurrence of hypoxemia and duration of supplemental oxygen administration during recovery from general anesthesia in bakers and smokers. ...

results roc-derived spo2 threshold of ≤ 94% can predict hypoxemia (pao2 < 60 mmhg) with a sensitivity of 100% and a specificity of 95%. furthermore, there are associations between the roc-derived spo2 threshold of ≤ 97% and detection of hypoxemia (pao2 < 70 mmhg) with a sensitivity of 100% and a specificity of 46%. the accuracy of pulse oximetry was not affected by the severity of liver disease...

BACKGROUND The objective of this study was to assess the feasibility and safety of heparin-free veno-venous extracorporeal life support (VV ECLS) as a means of salvaging polytrauma patients with life-threatening hypoxemia. METHODS This is a retrospective observational study on 7 consecutive trauma patients who underwent VV ECLS for severe chest trauma unresponsive to conventional measures. ...

Traumatic fat embolism syndrome occurs most often following fractures of long bones sustained in road traffic accidents and is a common cause of medical consultation from the orthopedic surgery department. The sub-clinical presentation is subtle and expresses itself by the presence of hypoxemia, while the full clinical syndrome compromises respiratory insufficiency, an altered consciousness and...

background and objective: the main causes of nocturnal hypoxemia are pulmonary diseases or sleep related breathing disorders. in overlap syndrome, the co-existence of chronic obstructive pulmonary disease (copd) and ob-structive sleep apnea (osa), blood oxygen alteration, and hypercapnia may be more severe. we aimed to study hypox-emia markers in osa patients with or without copd. materials and...

Despite many efforts, the pathophysiology and mechanism of blast-induced traumatic brain injury (bTBI) have not yet been elucidated, partially due to the difficulty of real-time diagnosis and extremely complex factors determining the outcome. In this study, we topically applied a laser-induced shock wave (LISW) to the rat brain through the skull, for which real-time measurements of optical diff...