Cysteamine administration to rats is followed by a high incidence of peptic ulceration. The aim of the present study was to investigate the effect of cysteamine on gastric and duodenal mucosal histamine and gastric mucosal histamine formation capacity. After a four hour fast, cysteamine in doses of 50, 100, 200, 300, 400, and 500 mg/kg bodyweight was injected subcutaneously to male Wistar rats;...

This case report describes a rare condition of lingual mucosal ulceration associated with bony sequestration following non-surgical lower molar tooth extraction healthy 58-year-old female patient. Clinically, she presented painful ulcer on the aspect posterior mandible and noticed sharp bone which caused irritation to side tongue. The exposed was removed surgically, completely healed. Thus, emp...

Oral mucosal ulceration is a common clinical complaint. Ulceration is often debilitating and affects patients from a wide age group. the clinician confronted with such a patient often feels overwhelmed by the different diagnostic possibilities. Given the wide spectrum of conditions encountered, it is striking that the common use of antibiotics and antifungals to treat oral ulceration, is largel...

Correlation of Visick grading was done with serial endoscopies in 19 patients operated for duodenal ulceration. Deeper mucosal lesions like ulceration showed good association with Visick grading (100%), while superficial mucosal lesions were mostly asymptomatic and therefore, caused disparity in grading. Moreover, as symptoms and endoscopic findings changed with passage of time, it was conclude...

Abstract Gastric ulcer is a common health issue. Cotinus coggygria heartwood extracts rich in the flavonoids fustin and sulfuretin have shown protective effects rat model of indomethacin-induced gastric ulceration. Fustin itself has been ethanol-induced ulcer. In present study we aimed to reveal effect flavonoid isolated from was purified. The experiment performed on 30 male Wistar rats allocat...

The association between cocaine use and acute gastroduodenal perforation is known. The effect of cocaine and stress on gastric mucosal ulceration and the levels of prostaglandin E(2) (PGE(2)) and leukotriene C(4) (LTC(4)) was studied in 40 Sprague-Dawley rats. Controls received intraperitoneal (i.p.) saline, ten received i.p. cocaine (35 mg/kg), ten were stressed by the cold restraint method, a...

INTRODUCTION Pemphigus vulgaris is a rare cause of oral mucosal ulceration. CLINICAL PICTURE A 47-year-old Chinese man presented with a 3-month history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris. TREATMENT Systemic and topical corticosteroids were instituted, together with topical antifun...

the patient is a 69 years old female presented with chest pain and rapidly progressive dysphagia. then she suffered of hematemesis and aphagia. in evaluation of patient, a intramural hematoma obstructing esophageal lumen was demonstrated which was accompanied with mucosal ulceration and bleeding. it appears that this complication occurred in the context of concomitant use of alendronate with as...

TYPE: Case Report TOPIC: Transplantation INTRODUCTION: Colonization and isolation of Aspergillus from bronchial specimens predisposes lung transplant (LTx) recipients to airway anastomotic complications allograft rejection. Post-LTx antifungal prophylaxis with voriconazole has been associated cutaneous malignancies. We report a case voriconazole-associated mucosal ulceration in an LTx recipient...