We read with interest the case report of Fuentes et al.1 concerning the use of a fiberoptic intubation method through a Laryngeal Mask Airway (LMA) in an infant with Treacher Collins Syndrome. I congratulate them on the presentation of the case. I would like to add some comments. Treacher Collins syndrome is an autosomal dominant other airway devices is incomparable. The combined use of airway ...

The gene mutated in Treacher Collins syndrome, an autosomal dominant disorder of facial development, has recently been cloned. While the function of the predicted protein, Treacle, is unknown, it has been shown to share a number of features with the highly phosphorylated nucleolar phosphoproteins, which play a role in nucleolar-cytoplasmic transport. In the current study, the murine homologue o...

BACKGROUND : Management of patients with Treacher Collins syndrome is complicated and involves multiple disciplines working in concert to achieve a common outcome. This article reviews the experience at the Australian Craniofacial Unit and describes the protocol for management. METHODS : Fifty patients were treated during the last 30 years. The records of these patients were reviewed to estab...

BACKGROUND Treacher Collins syndrome (TCS) is a rare disorder with different levels of severity due to congenital head and face abnormalities which affect language, orofacial musculature, voice and breadth, suction, chewing and swallowing functions. AIMS This paper objectifies to report a Treacher Collins syndrome patient, describing phonoaudiological changes that can be found in individuals ...

treacher collin’s syndrome (tcs) is a rare inherited condition characterized by bilateral and symmetric abnormalities of structures within the first and second bronchial arches. patients with tcs present a serious problem to anesthetists maintaining their airway as upper airway obstruction and difficult tracheal intubation due to severe facial deformity. because of retrognathia, airway manageme...

Treacher Collins syndrome (TCS) or Franceschetti syndrome is an autosomal dominant disorder of craniofacial development with variable expressivity. It is named after E Treacher Collins who described the essential components of the condition in 1900. Incidence of this syndrome is approximately 1 in 50,000 live births and it affects both genders equally. It affects structures which are derivative...

Figure 1. A polycyclic, papular eruption on the face. A 24-year-old transgender woman with Treacher-Collins syndrome (mandibulofacial dysostosis) and AIDS (CD4 + cell count, 151 cells/mm 3) presented with a 1-month history of a pruritic, mildly erythematous, polycyclic papular eruption distributed diffusely over her face. She had no history of any similar eruptions and no history of facial impl...

Neonates and small infants with craniofacial malformation may be very difficult or impossible to mask ventilate or intubate. We would like to report the fiberoptic intubation of a small infant with Treacher Collins Syndrome using the technique described by Ellis et al. CASE REPORT An one month-old infant with Treacher Collins Syndrome was scheduled for mandibular surgery under general endotra...