background: gastric cancer is an important health problem across the world. chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. the purpose of this investigation was evaluation of response and tolerability to neoadjuvant eox regimen in locoregionally advanced gastric cancer. materials and methods: patients with locoregionally adv...

helicobacter pylori is the main cause of gastric ulcer, adenocarcinoma and mucosa-associated lymphoid tissue (malt) lymphoma. up to now, different regimens have been used for helicobacter pylori (h.pylori) eradication to find the most potent and cost-effective regimen with less side effects. the aim of this study was to investigate the efficacy of standard triple therapy versus quadruple therap...

  Tuberculosis is still known as the most fatal disease of man caused by a single microbe.according to the report of world Health organizition ,contaminition of about half of the population of the world by My cobactrrium tuberculosis and nine million cases  of  tuberculosis anually as well as appearance of the resistant forms of tuberculosis has made it  one of the health diffeculties in the w...

background: several large clinical trials and meta-analyses have shown about 20% failure to eradicate helicobacter pylori ( h. pylori ), necessitating investigations for second-line treatments. the aim of this study was to evaluate the effects of clarithromycin-containing quadruple regimen after nitroimidazole-containing quadruple therapy failure. methods: thirty two patients who had failed 10-...

Background: Gestational trophoblastic neoplasia (GTN) originates from placental trophoblast and is a highly chemosensitive and curable gynecologic malignancy. The present study was conducted to evaluate the effectiveness and safety of EMA/EP (etoposide, methotrexate, actinomycin-D, etoposide, and cisplatin) regimen in the treatment of high-risk GTN as well as patients’ outcome.  &nb...

conclusions if such a regimen is approved, it would be a breakthrough in the treatment of hcv in subjects with hemoglobinopathy. more prospective, randomized control trial studies are needed to investigate the efficacy and safety profile of such a regimen. case presentation we described a 16- year-old male patient with sickle-thalassemia who was infected with a hcv. treatment was started with s...

A program has been written to run on a pocket computer (Sharp PC-1500) that can be used at the bedside to predict the nutritional requirements of patients with a wide range of clinical conditions. The predictions of the program showed good correlation with measured values for energy and nitrogen requirements. The program was used, with good results, in the management of over 100 patients needin...

background urinary tract infections (utis) are among the most commonly bacterial infections in clinical practice.almost half of all women experience at least one urinary tract infection in their lifetime. this study compared efficacy and safety of 3-day and 7-day ciprofloxacin regimen for the treatment of uncomplicated urinary tract infection in women. patients and methods a total of 76 patient...