The biocidal activity of 8 triorganotins R3S11X (R = butyl, phenyl, benzyl; X = oxide, chloride, acetate, naphthenate, TV, JV-diethyldithiocarbamate) on brown rot fungi, moulds mixture, benthic organisms, plankton alga Scenedesmus quadricauda, and crop plant has been investigated. The results suggest dependence between lipophilicity of bounded R groups and intensity of unfavourable effect. The ...

Organotin(IV) complexes with o- or p-hydroxybenzoic acids (o-H(2)BZA or p-H(2)BZA) of formulae [R(2)Sn(HL)(2)] (where H(2)L = o-H(2)BZA and R = Me- (1), n-Bu- (2)); [R(3)Sn(HL)] (where H(2)L = o-H(2)BZA and R = n-Bu- (3), Ph- (4) or H(2)L = p-H(2)BZA and R = n-Bu- (5), Ph- (6)) were synthesized by reacting a methanolic solution of di- and triorganotin(IV) compounds with an aqueous solution of t...

The formyl-meth-oxy-nitro-phenoxide ions in the polymeric title compound, [Sn(C(7)H(7))(3)(C(8)H(6)NO(5))](n), link adjacent triorganotin(IV) cations into linear chains lying close to (101) [Sn-O = 2.1227 (12) Å and Sn← O = 2.4936 (13) Å]. The Sn(IV) atom is displaced out of the C(3)Sn girdle of the trans-C(3)SnO(2) trigonal-bipyramidal polyhedron in the direction of the covalently-bonded O ato...

The synthesis, spectroscopic characterization and in vitro antitumour activity of two triorganotin compounds, triphenyltin ortho-aminophenylthiolate (1) and triphenyltin 2-pyridylthiolate, compound (2) are reported. The structure of 1 is confirmed by X-ray diffraction, with the tin atom in a distorted tetrahedral geometry because of monodentate coordination, as a thiolate (Sn-S 2.431(2) A), of ...

The in vivo toxicity profiles in mice and the antitumour activity in tumour bearing mice were screened for four di-n-butyltin and five triorganotin carboxylates, di-n-butyltin diterebate (5), bis(phenylacetate) (6), bis(deoxycholate) (7), bis(lithocholate) (8), tri-n-butyltin terebate (9), cinnamate (10), and triphenyltin terebate (11).At their maximum tolerated dosis (MTD), no antitumour effec...

Triorganotin compounds exhibit several modes of toxic action on the energy metabolism in energy-transducing membranes. The inhibition of the adenosine triphosphate (ATP) synthase and the hydroxide/chloride-antiport have been extensively investigated, but debate still exists on whether further mechanisms are relevant. In this work, two possible further effects have been investigated: inhibition ...