BACKGROUND Triple A syndrome (or Allgrove syndrome) is a rare autosomal recessive disorder characterized by alacrima, achalasia, adrenal insufficiency and autonomic/neurological abnormalities. The majority of cases are caused by mutations in the AAAS gene located on chromosome 12q13. However, the clinical picture as well as genetic testing may be complex since symptomatology is variable and mut...

Triple A syndrome (Allgrove syndrome) is an autosomal recessive disorder consisting of achalasia, alacrima and Addison insufficiency. We report an 11-year-old girl with predominant symptom of achalasia who was diagnosed as Triple A syndrome almost 3 years after initial presentation.

Toshihiro Tanizawa∗ Kochi National College of Technology, 200-1 Monobe-Otsu, Nankoku, Kochi 783-8508, Japan Abstract We examine two properties of complex networks, the robustness against targeted node removal (attack) and the transport efficiency in terms of degree correlation in node connection by numerical evaluation of exact analytic expressions. We find that, while the assortative correlati...

Behçet’s disease (BD) is a disease which has effects on different systems. Genital ulcer, aphthous stomatitis and iritis are characterized by triple symptom complex of BD. BD is considered to be a systemic vasculitis. BD was previously accepted in spondyloarthropathy (SSpA) group, but there are many reasons for not classifying BD as one of SSpA group. Ankylosing spondylitis (AS) is a prototype ...

PURPOSE Triple therapy with gabapentin, amitriptyline, and nonsteroidal antiinflammatory drugs is efficacious for chronic bladder pain syndrome/interstitial cystitis (BPS/IC). However, transient, fluctuating, worsening pain or flare-up symptoms may develop during treatment for a variety of reasons. Here, we assessed the validity of our observational experience regarding a short course of oral p...

Introduction The child’s history reveals frequent faringitis accompanied by oral lesions (4-5 episodes/year), billatreal ankle joint swelling and weight loss. Behçet disease (BD) is characterized by a triple-symptom complex of recurrent oral aphthous ulcers, genital ulcers, and uveitis. Hippocrates may have described Behçet disease in the fifth century BC; however, the first description of the ...