This paper describes a fully automated droplet-based microfluidic device for on-demand serial dilution that is capable of achieving a dilution ratio of >6000 (concentration ranges from 1 mM to 160nM) over 35 nanoliter-scale droplets. This serial diluter can be applied to high throughput and label-free kinetic assays by integrating with our previously developed on-demand droplet-based microfluid...

The presence of a distracting stimulus during performance of the Stroop color-naming task leads to dilution of the Stroop effect. Because the automatic activation of word meaning may interfere with the task-relevant stimulus feature (text color; stimulus-stimulus [S-S] interference) and the response (saying the text color; stimulus-response [S-R] interference), it is unclear which of these type...

with carry-over or drift. Automation of these RIA assays has halved the man-hours normally required and eliminated the many errors which can occur in the manual analysis and clerical reporting of large batches of specimens. One of the drawbacks of the system is that complete shutdown occurs when there is a printer failure. This fail-safe system is not essential when the analyser is connected to...

We propose a scenario where dark matter (DM) with wide mass range from few keV to PeV can be produced solely evaporating primordial black holes (PBH), while being consistent the required free streaming length for structure formation. If DM does not have any other interactions apart gravity and universe has PBH dominated phase at early epoch, then evaporation typically leads overproduction of in...

have considered this aspect in some detail for the analysis of vitamins. Accepted manual methods often do not correlate well with automatic analysis primarily because the operating conditions employed in a manual analysis lack the control of the automatic systems. The other significant problem is that components used in commercial instruments or which are readily available are not sufficiently ...

Low-Density Lipoprotein (LDL) extracted from egg yolk has recently known can eliminate the adverse effect associated in use of fresh yolk. The role LDL liquid preservation at 4°C ram sperm not been explored. This research evaluates effects substituting with 4 °C on 5 days. objective this was to assess for as an extender 4°C, well spermatozoa motility, viability, morphology, plasma membrane, and...

Macrocyclic tris-malonates incorporating cleavable di-tert-butylsilylene protecting groups have been prepared by a stepwise approach and used for the regioselective tris-functionalization of C60. Fullerene tris-adducts with an e,e,e addition pattern thus obtained. The bridging cleaved to liberate terminal alcohol functions fullerene tris-adduct. This key building block has further functionalize...