Objective(s): Detection of circulating Mycobacterium tuberculosis (M. tuberculosis) antigens is promising in Tuberculosis (TB) diagnosis. However, not a single antigen marker has been found to be widely expressed in all TB patients. This study is aimed to prepare broadly reactive polyclonal antibodies targeting multiple antigen markers (multi-target antibodies) and evaluate their efficacies in ...

In this paper, we present a mathematical model for the study of resistance to tuberculosis treatment using fractional derivatives in Caputo sense. This takes into account relationship between Tuberculosis, HIV/AIDS, and diabetes differentiates cases MDR-TB (multidrug-resistant tuberculosis) XDR-TB (extensively drug-resistant tuberculosis). We basic results associated with behavior disease-free ...

Background: Mycobacterium tuberculosis lipid antigens take part in pathogenicity of the bacterium but the response of monocytes/macrophages to these antigens in tubercu-losis is not well known. Objective: The aim of current investigation was to study the M. tuberculosis lipid antigens in tuberculosis pathogenesis. Methods: In the present study M. tuberculosis lipid antigens were extracted. Mono...

background the unregulated availability and irrational use of tuberculosis (tb) medicines is a major issue of public health concern globally. governments of many low- and middle-income countries (lmics) have committed to regulating the quality and availability of tb medicines, but with variable success. regulation of tb medicines remains an intractable challenge in many settings, but the reason...

Tuberculosis is an infectious disease caused by the germ Mycobacterium tuberculosis. The group of bacteria in addition to tuberculosis that can cause disorders airways known as MOTT (Mycobacterium Other Than Tuberculosis), which sometimes interfere with enforcement TB diagnosis and treatment. (TB) a high burden for Indonesia, not only because itself, but also its resistant several first-line dr...

tuberculosis is an infectious disease caused by mycobacterium tuberculosis and is the primary cause of mortality in the world. m. tuberculosis strains are important intracellular pathogens causing infection in oxygen-rich macrophages in the lungs. the emergence of aids, declined socioeconomic standards and a lessened emphasis on tb control programs have contributed to the disease resurgence. re...

miliary tuberculosis (tb) is due to hematogenous spread of mycobacterium tuberculosis. clinical manifestations are nonspecific and protean, depending on the predominant site of involvement.we evaluated the clinical manifestations of 15 patients with miliary tb. the diagnosis of miliary tuberculosis was based on the identification of miliary nodules on chest radiography and one of the three foll...

objective: antigen 85 complex of mycobacterium tuberculosis includes three immunogenic proteins which are important tb vaccine candidates. the use of these protein as a component of subunit vaccines, as a part of dna vaccines or recombinant bcg boosters, enhances their recombinant production. recombinant production of these mycobacterial proteins located in the cell wall somehow differs from th...

Background and objectives: Tuberculosis (TB) is the major public health problem in the world. Each year there are 2-3 million deaths worldwide caused by TB. The increasing incidence of Multi Drug Resistance tuberculosis (MDR-TB) worldwide highlights the urgent need to search for new anti-tuberculosis compounds. It has been reported that medicinal plant, Dracocephalum kotschyi, possesse...