INTRODUCTION Insulin resistance assessment requires sophisticated methodology of difficult application. Therefore, different estimators for this condition have been suggested. The aim of this study was to evaluate the triglycerides and glucose (TyG) index as a marker of insulin resistance and to compare it to the triglycerides/HDL cholesterol ratio (TG/HDL-C), in subjects with and without metab...

Insulin resistance (IR) is considered cardinal to the pathophysiology of metabolic syndrome (MetS). Previously, several simple indexes IR calculated from biochemical and anthropometric variables have been proposed. However, these are population-dependent; therefore, further studies on a global scale necessary. The present study assessed diagnostic accuracy eight indicators, namely, METS-IR, TG-...

INTRODUCTION Insulin resistance (IR) is a key molecular disorder related with diabetes mellitus, obesity, and cardiovascular disease. The objective of this study was to determine IR in adult primary care patients using the triglyceride/glucose (TyG) index [(Ln TG (mg/dL) × FG (mg/dL))/2]. METHODS We conducted a cross-sectional secondary analysis and identified IR subjects according to the TyG...

PURPOSE The prevalence rates of metabolic syndrome (MetS) and percentile distribution of insulin resistance (IR) among Korean children and adolescents were investigated. The cutoff values of IR were calculated to identify high-risk MetS groups. METHODS Data from 3,313 Korean subjects (1,756 boys and 1,557 girls, aged 10-18 years) were included from the Korean National Health and Nutrition Exa...

Background and Aims: Zonulin, carnitine, choline, g-butyrobetaine (g-BB), trimethylamine N-oxide (TMAO) are intricately involved in metabolic anomalies type 2 diabetes mellitus (T2D). This study aimed to compare correlate the plasma levels of zonulin, g-butyrobetaine, TMAO, along with adiposity, atherogenicity, surrogate insulin resistance (sIR), proinflammatory hematological indices newly diag...

Non-Alcoholic Fatty Liver Disease (NAFLD) is considered by many to be the hepatic manifestation of metabolic syndrome, the constellation of obesity, impaired glucose tolerance, dyslipidemia and hypertension that has been associated with a higher prevalence of NAFLD and Non-Alcoholic Steatohepatitis (NASH).1 Most patients with NAFLD are asymptomatic, with many of them suspected to have fatty liv...

Objective: The aim of the present study is assessment of insulin resistance (IR) in obese women by TyG-Index and compared with the HOMA-IR index. Materials and Methods: This cross-sectional study was performed on 61 obese women aged 18-45 years. Weights, height, waist circumference (WC) were measured and body mass index (BMI) was calculated and recorded. A sample of fasting serum was collecte...

BACKGROUND Plasma soluble cluster determinant 36 (sCD36) level is closely related with insulin resistance and atherosclerosis, but little is known whether it could be a surrogate for estimating risk of developing diabetes or not. To address this, we evaluated association between sCD36 index, the product of sCD36 and fasting plasma glucose (FPG), and the prevalence of type 2 diabetes mellitus (T...

BACKGROUND To directly compare traditional lipid ratios (total cholesterol [TC]/high density lipoprotein cholesterol [HDL-C], non-HDL-C/HDL-C, low density lipoprotein cholesterol [LDL-C]/HDL-C, and triglycerides [TG]/HDL-C), apolipoprotein B (apoB)/apolipoprotein A-I (apoA-I) ratio, visceral adiposity index (VAI), lipid accumulation product (LAP), and the product of TG and fasting glucose (TyG)...