objective(s): the aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-cd) and hydroxypropyl-β-cyclodextrin (hp-β-cd) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility.   materials and methods: phase solubility of aripiprazole with t...

  Objective(s): The aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility.   Materials and Methods: Phase solubility of ar...

hla-g is normally expressed on human trophoblast cells. it is a non-classical mhc molecule class i b. the role of hla-g in diabetic type 1 is not known. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dendritic cells (dc) in diabetes type 1. treatment of dendritic cell with ifn-β in vitro from diabetic patients (n=20) and normal subjects (n=20) resulted t...

background leptin, a protein released from adipose tissue, could have significant role in pathogenesis of obesity and type 2 diabetes mellitus. conclusions it is speculated that lower serum leptin levels in diabetic patients may be a consequence of male gender. moreover, results suggest that serum leptin level in women is influenced differently than that in men. results the serum leptin level i...

allergic asthma is a complex and chronic inflammatory airway disease. interleukin-17 is a pro-inflammatory cytokine which plays critical role in the pathogenesis of allergic asthma. it has been reported that β-arrestin2 regulated the development of allergic asthma at a proximal step in the inflammatory cascade. in this study, the influence of β-arrestin2 on interleukin-17 production and express...

The purpose of this paper is to solve the seventh-order functional equation as follows:  --------------------------- Next, we study the stability of this type of functional equation. Clearly, the function ----------  holds in this type functional equation. Also, we prove Hyers-Ulam stability for this type functional equation in the β-Gaussian Banach space.  

conclusions according to the results of this study, we can conclude that our suggested model is suited to explaining the pathways of stress among iranian male staff. results a total of 575 individuals (all male) were recruited for the study. their mean (±sd) age was 33.49 (±8.9) and their mean job experience was 12.79 (±8.98) years. the pathway of job stress among iranian male staff showed an a...