how to cite this article: salehpour sh. clinical manifestations of type 1 gaucher disease. iran j child neurol autumn 2012; 6:4 (suppl. 1):13-14. pls see pdf. refe r ences 1. beutler e, grabowski ga. gaucher disease. in: metabolic and molecular bases of inherited disease, scriver cr, beaudet al, sly ws, valle d (eds), mcgraw-hill, new york 2001: 3635. 2. cox tm, schofield jp.   gaucher’s diseas...

background : type 1 diabetes mellitus is the most common endocrine disease in pediatric. we aimed to determine the demographic characteristics at presentation of childhood type 1 diabetes mellitus in hamadan, west province of iran. methods : in this cross sectional descriptive study, demographic data of children with type 1 diabetes mellitus being followed up in pediatric endocrinology clinic o...

introduction: glutaric academia type i is a metabolic disorder that is caused due to deficiency of glutaryl-coa dehydrogenase. macrocephaly is a common sign in ga1, although many infants usually appear healthy at birth.   case report a 5.5 year old boy with ga1was admitted to nicu. chief compliance of patient for hospitalization was pneumonia and sepsis and he was intubated and mechanically ven...

objective(s):pentoxifylline is an immunomodulatory and anti-inflammatory agent and is used in vascular disorders. it has been shown that pentoxifylline inhibits proinflammatory [d1] cytokines production. the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune diabetes in mice. materials and methods: diabetes was induced by multiple l...

ramadan fasting is an important pillars of islam .although patients and children expected from fasting during ramadan, but every diabetic adolescents intends to fast should consult his diabetes management time, and intensive monitoring of blood glucose and urine ketones .close observation by endocrinologist, and weekly follow- up and highly individualized planning for each diabetic person is es...

background type 1 diabetes mellitus is one of the metabolic diseases that cause insulin-producing pancreatic ß cells be destroyed by immune system self-reactive t cells. recent­ly, new treatment methods have been developed including use of the stem cells, ß islet cells transplantation and gene therapy by viral and non-viral gene constructs. objectives the aim of this project was preparing the n...

conclusions parental functioning and wellbeing are important aspects of a family adaptation to chronic pediatric conditions. moreover, psychological interventions were recommended to patients. results the abbreviation (gsi) score in leukemic children’s mothers was higher than t1dm children’s mothers and both groups had higher gsi compared with the control group. background parents’ psychologica...

the aim of this study was to find out whether there is seasonality of month of birth in children with diabetes in mashhad and if so whether it differs from that of general papulation. 161 children and adolescents (0-18 years) with type 1 diabetes born between 1983-2001 were included the study. the results were analyzed by student’s t test and chi-square test and a p value<0.05 was considered si...

background: stem-cell technology has been advocated as a potentially curative option for treatment of both type 1 and type 2 diabetes. in the current study, we aimed to assess the effectiveness of allotransplantation of fetal liver-derived cells for treatment of patients with type 1 diabetes. methods: for the purpose of the current study, 72 patients with recently diagnosed type 1 dm were recru...

conclusions managing t1dm in the context of exercise or athletic competition is a challenging but important skill for athletes living with this disease. a proper understanding of the hormonal milieu during exercise, special nutritional needs, glycemic control, necessary insulin dosing adjustments, and prevention/management strategies for exercise-related complications can lead to successful car...