metabolic syndrome and its pathological sequel, type 2 diabetes are considered as important global health problems. metformin is the most common drug prescribed for patients with this disorder. consequently, understanding the genetic pathways involved in pharmacokinetics and pharmacodynamics of this drug can have a considerable effect on the personalized treatment of type 2 diabetes. in this st...

background : joint proprioception plays an important role in limb movement and awareness of position sense. diabetes has a lot of complications such as lossof sensoryfunction, which canleadtoimpaired balance, thus the aim of this study to evaluated joint proprioception and balance in diabetic patients. methods: twenty type ii diabetic patients and20healthy controls participated in this case-con...

Introduction To define the clinical features, biochemical and histological findings and outcome of three forms of autoimmune hepatitis.   Materials and Methods In a cross sectional study between November 2001 to January 2008 in Tehran and Mashhad university of medical sciences, 61 children who diagnosed as AIH (40 girls and 21 boys) have been analyzed for their clinical, serological, and histol...

background: considering the effect of socioeconomic factors on the appearance of chronic diseases, and also the importance of this issue for policy makers of health care services, we tried to assess the role socioeconomic factors have in diabetes complications. this survey may have some benefits in prevention and control of diabetes.   methods: this cross-sectional study was conducted on 384 di...

background: diabetes is a common disease that can lead to metabolic abnormalities and chronic complications. today, the positive role of physical activity and exercise, especially walking in health human society and has been approved in prevention and control many complications including diabetes. today, the positive role of physical activities and exercise , especially hi wal king in the healt...

objective: the aim of this study was to evaluate the effect of zinc and magnesium supplementation on glycemic control and serum insulin in type 2 diabetic patients. materials and methods: in this randomized clinical trial 70 diabetic patients who referred to yazd diabetes center were selected. subjects received 500 mg/day magnesium oxide or 100 mg/day zinc sulfate randomly for 8 weeks. at the s...

objective: type 2 diabetes is amongst the most common chronic illnesses in iran. its prevalence is increasing and it has significant economic importance. the aim of this study was to estimate direct therapeutic and non-therapeutic costs of type 2 diabetes patients referred to the diabetes research center of yazd in 2012. materials and methods: this cross-sectional study was carried out on 250 t...

background: to evaluate the efficacy of adding the glutazone to maximum dose of sulfonylurea and metformin in patients with poorly controlled type 2 diabetes. methods: ninety six patients with type 2 diabetes who had failed medical therapy with maximal-dosage of metformin and glibenclamide received glutazone. fasting blood sugar (fbs), 2 hours postprandial (2hpp) glucose, hemoglobin a1c, choles...

background: the prevalence and complications of type2 diabetes showed that traditional educations are not effective. in this trial, we evaluated the effect of electronic self-care education and continue case in compare to the traditional training methods on the practice and fasting blood sugar of diabetic patients. methods: 170 type 2 diabetic patients were randomly allocated into two groups an...

conclusions our study showed a significant association between h63d and c282y mutations and the risk of type 2 diabetes in iranian population. background type 2 diabetes (t2d) is a common metabolic disease caused by insulin secretion defects, which is associated with a variety of complications such as retinopathy, nephropathy, and neuropathy. objectives regarding the relationship between type 2...