The user mobility pattern (UMP) scheme is introduced for location update and paging in wireless systems where mobile terminals (MTs) maintain their history data in a database called user mobility history (UMH). During a location update, a UMP is derived from UMH and registered to the network. Unless the MT detects that it has moved out of the registered UMP, it does not perform any other locati...

Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK);EC 2.7.4.14] plays a crucial role in the formation of UDP, CDP, and dCDP, which are required for cellular nucleic acid synthesis. Several cytidine and deoxycytidine analogues are important anticancer and antiviral drugs. These drugs require stepwise phosphorylation to their triphosphate forms to exert their therapeutic effect...

Mono- and polyclonal antibodies directed against UMP kinase from Escherichia coli were tested with the intact protein or with fragments obtained by deletion mutagenesis. As detected in enzyme-linked immunosorbent assay tests, the carboxy-terminal quarter of UMP kinase is immunodominant. Polyclonal antibodies inhibited the enzyme activity with partial or total loss of allosteric effects exerted ...

BACKGROUND Human UMP/CMP kinase was identified based on its enzymatic activity in vitro. The role of this protein is considered critical for the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells, based on the in vitro study of partially purified enzyme and recombinant protein. However, no detailed study has yet addressed the role of this pro...

The existing imbalance compensation strategies for magnetic suspension motors mainly focus on the mass unbalance force, ignoring effects of unbalanced magnet pull (UMP). This paper studied vibration mechanism and strategy suspended permanent synchronous motor (PMSM) under influence UMP. Firstly, an analytical model flux density was established based equivalent circuit method, then expressions U...

We examined the biochemical pathways whereby oral uridine-5'-monophosphate (UMP) increases membrane phosphatide synthesis in brains of gerbils. We previously showed that supplementing PC12 cells with uridine caused concentration-related increases in CDP-choline levels, and that this effect was mediated by elevations in intracellular uridine triphosphate (UTP) and cytidine triphosphate (CTP). In...

Phosphorylation of deoxycytidine analogs by cellular enzymes is a prerequisite for the activity of these compounds. We have investigated the kinetic parameters for the phosphorylation of 1-beta-D-arabinofuranosylcytosine (araC) and 2', 2'-difluorodeoxycytidine (dFdC) to their diphosphate forms catalyzed by human UMP-CMP kinase. We cloned the cDNA of this enzyme to enable characterization of the...

bstract—Synthesis of phosphatidylcholine, the most abunant brain membrane phosphatide, requires three circulating recursors: choline; a pyrimidine (e.g. uridine); and a polynsaturated fatty acid. Supplementing a choline-containing iet with the uridine source uridine-5=-monophosphate (UMP) r, especially, with UMP plus the omega-3 fatty acid docosaexaenoic acid (given by gavage), produces substan...

This paper presents a new voice activity detection (VAD) method using the Gaussian distribution and a uniformly most powerful (UMP) test. The UMP test is employed to derive the new decision rule based on likelihood ratio test (LRT). This method requires the Rayleigh distribution for the magnitude of the noisy spectral component and the adaptive threshold estimated from the noise statistics. Exp...

for the enzyme in vivo unless an alkaline micro-environment was postulated or conditions were present in vivo which could potentiate inhibition by UMP at near-neutral pH (Yon, 19726). Substances such as deoxycholate which can bind to the hydrophobic site on the enzyme may provide such potentiation. Fig. 2 shows the effects of UMP and deoxycholate at pH values between 7 and 11. In the absence of...