BACKGROUND Patients with unprovoked venous thromboembolism (VTE) are at an increased risk of mortality, but whether their cardiovascular risks also increase remains to be determined. We aimed to investigate the factors associated with overall mortality and major adverse cardiovascular events in patients with unprovoked VTE. METHODS AND RESULTS We identified 2154 patients newly diagnosed with ...

Treatment issues following a first unprovoked seizure are discussed, using an approach that emphasizes weighing the relative risks and benefits of the therapeutic decisions. The majority of children and adults who present with a first unprovoked seizure will not experience further seizures. Both seizures and the therapies available carry some risk, and optimal patient care requires careful bala...

BACKGROUND Increasing numbers of reports show the beneficial effects of listening to Mozart music in decreasing epileptiform discharges as well as seizure frequency in epileptic children. There has been no effective method to reduce seizure recurrence after the first unprovoked seizure until now. In this study, we investigated the effect of listening to Mozart K.448 in reducing the seizure recu...

BACKGROUND AND OBJECTIVES Prospective data are lacking to determine which children might benefit from prompt neuroimaging after unprovoked seizures. We aimed to determine the prevalence of, and risk factors for, relevant intracranial abnormalities in children with first, unprovoked seizures. METHODS We conducted a 6-center prospective study in children aged >28 days to 18 years with seemingly...

The provocative effects of sleep deprivation (SD) on patients with seizure disorder and on the electroencephalogram (EEG ) are well known. The purpose of the study was to test its routine use and usefulness in the pediatric and adolescent age group with, or suspect of having, seizure disorder, especially those presenting with first unprovoked seizure. Between September 2000 and November 20...

introduction: seizure is the most common pediatric neurology problem that occurs in 10% of children. the purpose of this study was to determine the recurrence rate of seizures after one year and its relationship with paraclinical findings of the first attack. methods : in a historical cohort analytic study , 131 children with first seizure admitted to shaheed sadoughi hospital between march 200...

Previous studies that operationalized reactive aggression using behavioral observations in general populations have not taken into account the type of stimulus that elicits reactive aggression. In the present study we define a specific form of reactive aggression, i.e., reactive aggression in response to neutral behavior of a peer, which we will call unprovoked reactive aggression. We were spec...

objective most children brought to the emergency department (ed) for evaluation of seizures undergo an extensive laboratory workup. since results are usually negative, the value of such routine laboratory workups has been questioned. a group of children with unprovoked seizures was prospectively studied to determine the diagnostic values of routine serum chemistries and to identify risk factors...

objective the first attack of unprovoked seizure is more frequent than recurrent one and neuroimaging is one of the main parts of the evaluation of these attacks in order to demonstrate the cause and predict the prognosis. the aim of this study was to determine the incidence of abnormal neuroimaging and related factors in children with the first unprovoked seizure. materials & methods a 7-year ...

1. Bonnett LJ, Marson AG, Johnson A, Kim L, Sander JW, et al. (2014) External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving. PLoS ONE 9(6): e99063. doi:10.1371/journal.pone.0099063 Citation: The PLOS ONE Staff (2014) Correction: External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoke...