Recent work has shown how comparative genomic and microarray analyses can provide insights into the transcriptional state of uropathogenic Escherichia coli (UPEC) during infection. This study will serve as an important platform from which to identify virulence determinants and the principle mechanisms of adaptation to the urinary tract.

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Escherichia coli is the most common bacterium causing urinary tract infections in humans. We report here the complete genome sequence of the uropathogenic Escherichia coli strain NU14, a clinical pyelonephritis isolate used for studying pathogenesis.

background and objectives: urinary tract infection (uti) is one of the most common infections in human, and uropathogenic escherichia coli (upec) strains are the most common cause of uti. these strains colonize in bladder and cause cystitis, which could cause pyelonephritis by movement to the kidneys. since fimh protein has a very important role in colonization of upec strains and causing infec...

Citation: Demirel I, Persson A, Brauner A, Särndahl E, Kruse R and Persson K (2018) Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells. Front. Cell. Infect. Microbiol. 8:81. doi: 10.3389/fcimb.2018.00081 Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli ...

Objective(s): Escherichia coli is the key pathogen in the family producing ESBL (extended spectrum β-lactamase) and associated with community-acquired infections. Therefore, this study was planned to determine the antibiotic susceptibility pattern of uropathogenic E. coli, prevalence of the ESBL gene group and class 1 integrons.Materials and Methods: Clinical isolates of uropathogenic E. coli w...

conclusions the trat gene and pai markers were highly prevalent among upec strains isolated from patients in kashan, iran; therefore these determinants could be used as targets for prophylactic interventions. also there was a high level of resistance against the antibiotics commonly used for urinary tract infection treatment. to reach better therapeutic outcomes, treatment regimens have to be m...

background: n-acyl homoserine lactone (ahl) is found to be the main component of quorum sensing (qs) in gram-negative bacteria and plays an important role in biofilm formation. little information is available regarding the role of ahl in biofilm formation in escherichia coli (e. coli). the purpose of this investigation was to biochemically detect and characterize ahl activity in biofilm-forming...

Background and Objectives: Recently, the use of probiotics for the treatment of Urinary Tract Infections has become more popular. The use of probiotics in therapy is useful as only a few side effects such as destruction of resistant bacteria or disturbance of the intestinal microbiota have been reported. The aim of this study was to evaluate the probiotic effects of lactic acid bacteria by co-a...