Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...

A meta-analysis was performed in an attempt to clarify the proposed relationship between religiosity and psychological adjustment. Specific focus was given to the issue of definition, namely, whether differences in researchers’ conceptualizations of religiosity and mental health could account for the various contradictory findings by psychologists of religion. Analysis of 34 studies conducted d...

Less than a decade after the founding of the American Pharmaceutical Association, the noted American physician Oliver Wendell Holmes, addressing the Massachusetts Medical Society in 1860, made his oft-quoted statement that " ...if the whole materia medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind-and all the worse for the fishes. " 1 The pharma...

An automated reasoning program has provided invaluable assistance in answering certain previously open questions in mathematics and in formal logic. These questions would not have been answered, at least by those who obtained the results, were it not for the program's contribution. Others have used such a program to design logic circuits, many of which proved superior (with respect to transisto...

In 1944 the Association for Education in Citizenship published a pamphlet entitled ‘Health’ by Major Jerry Morris1 (of the Royal Army Medical Corps), as one of a series of Handbooks for Discussion Groups. The preface to the pamphlets in this series said that they were intended to be used by discussion circles concerned with the social, economic and political problems that arose from the Second ...

Marijuana is a currently illegal psychoactive drug that many physicians believe has substantial therapeutic uses. The medical literature contains a growing number of studies on cannabinoids as well as case studies and anecdotal reports suggesting therapeutic potential. Fifteen states have passed medical marijuana laws, but little is known about the growing population of patients who use marijua...

The therapeutic use of ultrasound contrast agents (UCAs) is an emerging methodology with high potential for enhanced directed therapeutic gene, bioactive gas, drug, and stem cell delivery. Ultrasound-targeted microbubble destruction has already demonstrated feasibility for plasmid DNA delivery. Similarly, therapeutic ultrasound for thrombolysis treatment has been taken into the clinical setting...