نتایج جستجو برای: ussc

تعداد نتایج: 58  

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده علوم 1392

فاکتور رشد عصبی به عنوان عضوی از خانواده نوروتروفینها نقش مهمی در حفظ و ترمیم انواع نورونها ایفا می کند. جهت غلبه بر موانع استفاده موضعی از این فاکتور بعنوان دارو، پیوند سلولهای حامل ژن این فاکتور به محل آسیب دیده می تواند روش مناسبی باشد. سلولهای بنیادی تنه ای نامحدود یا ussc بعنوان زیر گروهی از سلولهای بنیادی موجود در خون بند ناف ویژگیهای مناسبی جهت استفاده در ژن درمانی دارا می باشند و نتایج ...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
saeed heidari-keshel mostafa rezaei-tavirani esmaeil biazar nayb ali ahmadi maryam ebrahimi abdolaziz ronaghi

background: for tissue engineering of bone, anatomical and operational reconstructions of damaged tissue seem to be vital. this is done via reconstruction of bone and appropriate biological joint with bone tissues of damaged areas. in this study the condition of biodegradable bed nano fiber phbv and ussc cells were used to accelerate bone repair of damaged area. methods: hollow nanofabrication ...

Journal: :Stem cells and development 2010
Aneta M Schaap-Oziemlak Reinier A Raymakers Saskia M Bergevoet Christian Gilissen Bastiaan J H Jansen Gosse J Adema Gesine Kögler Carlos le Sage Reuven Agami Bert A van der Reijden Joop H Jansen

Unrestricted somatic stem cells (USSCs) have been recently identified in human umbilical cord blood and have been shown to differentiate into lineages representing all 3 germ layers. To characterize microRNAs that may regulate osteogenic differentiation of USSCs, we carried out expression analysis for 157 microRNAs using quantitative RT-PCR before and after osteogenic induction (t = 0.5, 24, 72...

Journal: :iranian journal of immunology 0
hasan ebrahimi department of molecular medicine, pasteur institute of iran, tehran, iran masoud soleimani department of hematology, tarbiat modares university, tehran, iran mohammad kazemi arabadadi department of microbiology, hematology and immunology, faculty of medicine, rafsanjan university of medical sciences, rafsanjan, iran naser ajmadbeigi stem cell department, stem cell research center, tehran, iran gholamhossein hassanshahi department of microbiology, hematology and immunology, faculty of medicine, rafsanjan university of medical sciences, rafsanjan, iran akbar farjadfar department of molecular medicine, pasteur institute of iran, tehran, iran derek kennedy

background: unrestricted somatic stem cells (ussc) are cord blood stem cells that have been considered as candidates for the regulation of immune responses. therefore, potential exists for their use in the suppression of immune response after transplantation surgery. objective: the aim of this study was evaluation of the effect of ussc on mixed lymphocyte reaction (mlr) as a model for graft rej...

2013
Zahra Sadat Hashemi Mahdi Forouzandeh Moghadam Masoud Soleimani

OBJECTIVE(S) Ex vivo expansion of hematopoitic stem cells is an alternative way to increase umbilical cord blood (UCB)-CD34+ cells for bone marrow transplantation. For this purpose demineralized bone matrix (DBM) and mineralized bone allograft (MBA) as two scaffolds based on bone matrix and stem cell niche, were simultaneously used to enhance the effect of human mesenchymal progenitor cells (MP...

2014

Construction of the Linked Dataset: The primary data for this analysis are restricted-use data collected by the Bureau of Justice Statistics (BJS) and made available to researchers via the National Archive of Criminal Justice Data. 1 Using the restricted-use dyadic linking files provided by BJS, we link case records across agencies as they go through the criminal justice process, enabling us to...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008
Steffen Rabald Grit Marx Brigitte Mix Caspar Stephani Manja Kamprad Michael Cross Johannes Boltze Wilfried Briest Heinz-Gerd Zimmer Alexander Deten

OBJECTIVE In this study the ability of unrestricted somatic stem cells (USSC) and mononuclear cord blood cells (MN-CBC) was tested to improve heart function and left ventricular (LV) remodeling after myocardial infarction (MI). METHODS The cells were delivered by i.v. or intramyocardial injections in rat models of MI by permanent coronary artery occlusion and by ischemia/reperfusion (I/R) inj...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس 1387

چکیده مقدمه: پیوند آلوژنیک با خون بند ناف در بالغین عمدتاً به علت دوز پایین سلولهای cd34+ دارای محدودیت هایی است. برای غلبه براین محدودیت، می-بایست این سلولها مورد تزاید قرار بگیرند که جفت انسان به عنوان منبع جدیدی از سلولهای پروژنیتور مزانشیمی یعنی سلولهای بنیادی سوماتیک غیرمحدود شده(ussc) ، مورد بررسی و کاربری جهت استفاده به عنوان لایه مغذی برای سیستم کشت دکستر جهت تزاید سلولهای cd34+ خون ب...

Journal: :The International Journal of Human Rights 2021

The European Court of Human Rights (ECtHR) and the US Supreme (USSC) have emphasised foundational importance freedom expression. However, when exercise this liberty appears to endanger democratic institutions or national security state, readiness uphold limitations right increases. Over years each judicial body has adopted a distinctive approach towards on dangerous speech. Constitution envisag...

Journal: :The Journal of Experimental Medicine 2004
Gesine Kögler Sandra Sensken Judith A. Airey Thorsten Trapp Markus Müschen Niklas Feldhahn Stefanie Liedtke Rüdiger V. Sorg Johannes Fischer Claudia Rosenbaum Susanne Greschat Andreas Knipper Jörg Bender Özer Degistirici Jizong Gao Arnold I. Caplan Evan J. Colletti Graça Almeida-Porada Hans W. Müller Esmail Zanjani Peter Wernet

Here a new, intrinsically pluripotent, CD45-negative population from human cord blood, termed unrestricted somatic stem cells (USSCs) is described. This rare population grows adherently and can be expanded to 10(15) cells without losing pluripotency. In vitro USSCs showed homogeneous differentiation into osteoblasts, chondroblasts, adipocytes, and hematopoietic and neural cells including astroc...

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