A simple programmed thaw cycle is described, during which the endometrium is prepared with oral oestradiol, followed by a natural progesterone source. This method involves minimal blood tests and uses inexpensive medications. Originally, an i.m. progesterone-in-oil preparation was used. Although highly successful in achieving high serum progesterone concentrations, the daily injections of the o...

Correspondence: Jerome H Check 7447 Old York Road, Melrose Park, PA 19027 Tel +1 215 635 4156 Fax +1 215 635 2304 email [email protected] Abstract: Supplementation of progesterone in the luteal phase and continuance of progesterone therapy during the first trimester has been found in several studies to have benefits in promoting fertility, preventing miscarriages and even preventing pre-term lab...

background: preterm birth is the major cause of neonatal mortality and morbidity. objective: the aim of this study was to evaluate the effect of prophylactic vaginal progesterone on decreasing preterm birth rate and neonatal complications in a high-risk population. materials and methods: a randomized, double-blind, placebo-controlled study was performed on 100 high-risk singleton pregnancies. v...

Introduction Intramuscular and vaginal progesterone are recommended for prevention of preterm labor (PTL) in women with risk factors. Studies are emerging to indicate that HIV-infected women on combination antiretroviral therapy (cART) are at risk of PTL and low birth weight (LBW), and may benefit from supplemental progesterone. This study aims to determine the perceived acceptability of variou...

OBJECTIVE To compare severity of negative mood and physical symptoms between women with different progesterone, allopregnanolone, and pregnanolone plasma concentrations during sequential Hormone Replacement Therapy (HRT) with vaginal progesterone suppositories. DESIGN A randomized, placebo-controlled, double-blind, crossover study. METHOD Postmenopausal women (n=36) with climacteric symptom...

Supplementation of progesterone in the luteal phase and continuance of progesterone therapy during the first trimester has been found in several studies to have benefits in promoting fertility, preventing miscarriages and even preventing pre-term labor. Though it can be administered orally, intramuscularly or even sublingually, a very effective route with fewer side effects can be achieved by a...

OBJECTIVE To compare progesterone concentrations in serum and endometrial tissue from hysterectomy specimens after vaginal or intramuscular (IM) administration of progesterone gel. METHODS This was a randomized open study of 14 post-menopausal women undergoing transabdominal hysterectomies. Participants received either vaginal progesterone gel, 90 mg, or IM progesterone, 50 mg, at 8:00 AM and...

Different routes of natural progesterone supplementation have been tried as luteal phase support in infertility treatments. Orally administered progesterone is rapidly metabolized in the gastrointestinal tract and its use has proved to be inferior to i.m. and vaginal routes. Progesterone i.m. achieves serum progesterone values that are within the range of luteal phase and results in sufficient ...

Abortus imminens adalah perdarahan yang terjadi sebelum usia kehamilan 20 minggu, tanpa keluarnya janin. Selama kehamilan, progesteron berperan dalam proses implantasi janin ke rahim. Beberapa penelitian menunjukkan bahwa bermanfaat penanganan abortus imminens, baik bentuk oral maupun supositoria. Sediaan terbukti lebih efektif dibandingkan vaginal.
 Threatened miscarriage or imminent abor...