PURPOSE We aimed to assess the technical feasibility of targeted endovenous treatment of Giacomini vein insufficiency (GVI)-associated varicose disease and report our early results. METHODS We retrospectively screened 335 patients with varicose disease who underwent endovenous laser ablation from September 2011 to January 2013, and determined 17 patients who underwent Giacomini vein ablation....

Aim: To comparative analysis of vein stripping versus no in varicose disease. Study design: Comparative study Place and duration study: Department Surgery, CMH Kharian Medical College, from 01-01-2019 to 31-12-2021. Methodology: Eighty cases which were having sapheno-femoral valve incompetence as well perforators-incompetence enrolled. The age the was between 16 70 year. Electrocardiography (EC...

The Aberdeen Varicose Vein Questionnaire (AVVQ) is validated and frequently used as a patient-reported disease-specific quality of life (QoL) outcome in trials of varicose veins. The AVVQ comprises a manikin diagram where patients draw their varicose veins and 12 questions including pain, skin changes, use of support stockings, appearance and impact. AVVQ scores range from 0 to 100 (worst possi...

Varicose veins affect approximately one-third of the adult population and result in significant psychological, physical, and financial burden. Nevertheless, the molecular pathogenesis of varicose vein formation remains unidentified. Venous hypertension exerted on veins of the lower extremity is considered the principal factor in varicose vein formation. The role of mechanotransduction of the hi...

BACKGROUND Clinical assessment and prognostic stratification of primary varicose veins have remained controversial and the molecular pathogenesis is unknown. Previous data have suggested a contribution of the MTHFR (methylenetetrahydrofolate reductase) polymorphism c.677C>T. METHODS We collected blood and vein specimens from 159 consecutive patients undergoing varicose vein surgery, or autolo...

This study was designed to evaluate the role of the smooth muscle cell and the apoptosis in the pathogenesis of the varicose vein. Segments of saphenous vein were obtained from healthy subjects and from those with varicose veins. The vein specimens were subdivided according to subject age (younger or older than 50 years) and according to the varicose vein source (distal or proximal). Morphologi...

BACKGROUND Varicose veins affect up to 40% of men and up to 51% of women. The pathophysiology of primary varicosis is poorly understood. Theories ranging from incompetence of the venous valves to structural changes in the vein wall have been proposed. METHODOLOGY/PRINCIPAL FINDINGS We analyzed the functional state of the intramural smooth muscle cells (n = 14 pairs matched for age and gender)...

BACKGROUND Varicose veins are prominent dilated veins in the lower limb primarily due to disease in the junction between superficial and deep venous system. Operative treatment of such condition significantly improves quality of life and also demonstrably decreases the potential complications. We present with analysis of fifty one consecutive open surgeries for varicose vein at Dhulikhel Hospit...

background: venous diseases including varicose veins and chronic venous insufficiency are one of the most important pathogenic factors worldwide. high prevalence of varicose veins and its complications is an emerging problem in the twenty-first century. this study aimed to determine the prevalence and associated risk factors of varicose veins in female hairdressers in shahroud, north of iran in...