BACKGROUND We have developed a method of high magnification bronchovideoscopy that enables improved observation of subepithelial vascular patterns of the bronchial mucosa. A study was undertaken to investigate the value of high magnification bronchovideoscopy in the detailed examination of dysplasia in the bronchial mucosa of patients with abnormal mucosal fluorescence. METHODS Thirty one pat...

Background: There have been no studies to date on the pathophysiologic mechanisms of how fibromuscular dysplasia (FMD) affects vascular function. Due to the perturbations in the blood vessel wall and the propensity for stenosis, dissection, and aneurysms seen in arteries with FMD, subjects with FMD may have impairment in endothelial function and abnormalities in arterial compliance. Methods: Tw...

Background & objective Changes in submucosal vascularization and inflammation, determined by immunohistochemistry staining, were shown to be correlated with the development of dysplasia and invasiveness of epithelial cells in premalignant and malignant lesions. This study evaluated changes in sections routinely stained with Hematoxylin and Eosin (H&E) in order to investigate vascular density an...

BACKGROUND AND PURPOSE The association of cortical organization disorders with facial hemangiomas or vascular malformations has been described in only a few reports. The purpose of this study was to show the close association of these cutaneous anomalies with cortical dysplasias and intracranial vascular abnormalities. MATERIALS AND METHODS Five patients, all women, with cutaneous vascular ab...

The syndrome of undifferentiated connective tissue dysplasia ( U CTD) is a genetically determined condition, the detailed clinical picture which formed during first five years life. development vegetative-vascular dystonia in UCTD associated with changed collagen structure, leads to appearance numerous manifestations that affect psycho-emotional status child, especially if leading anxiety. purp...

Fibromuscular dysplasia is a nonatherosclerotic and non-inflammatory vascular disease with primary lesion of renal and internal carotid arteries. We present a neonatal case of fibromuscular dysplasia who died on the second day of life. The newborn suffered from fibromuscular dysplasia of the coronary arteries and a congenital heart defect. The interesting feature of this case was the formation ...

Incontinentia pigmenti is a very rare X-linked dominant inherited disease characterized by skin lesions, retinal pathologies, central nervous system anomalies, and dental problems. Norrie recessive severe vitreoretinal dysplasia in both eyes at birth. In diseases, patients can apply to the clinic with nystagmus, leukocoria, microphthalmia, detachment an early age. this review, disease, which ar...

A 47-year-old man presented with intussusception of the colon and was found to have a large tubulo-villous adenoma high grade dysplasia, transforming into adenocarcinoma. The bowel adjacent polyp showed florid vascualr proliferation, mimicking vascular neoplasm. However, there were no signs atypia or malignancy in lesion. We illustrate an example chronic obstruction inducing hypoxia, leading ne...