with the eight sassanians reliefs, naghsh-e rustam in marvdasht is a prominent complex safeguarding a complete collection of the sassanian period. seven of these reliefs have been repeatedly the subject of investigations thanks to their relatively better conditions. the fifth relief, however, has not yet been studied due to their damaged status. it depicts the full-face portrait of a sassanid k...

Alireza Aslani 2 1 Department of Nanobiotechnology Research Center, Baqiyatallah University Medical of Science, Tehran, Islamic Republic of Iran, P. O. BOX: 19945-546, Tel: +98-9161161165, Email: [email protected], [email protected] . 2 Department of Chemistry, Faculty of Basic Science, Jundi Shapur University of Technology, Dizful, Islamic Republic of Iran, P. O. BOX: 64615-334, Tel:...

PURPOSE To evaluate the effects of alprostadil in an experimental model of ischemia and reperfusion injury (IRI) in rat renal tissue. METHODS Adult male Wistar rats were randomized into three groups Vehicle-treated group(Veh), Alprostadil-treated(Al), and sham(Sh) group. Veh and Al groups had suprarenal aorta occluded for 30 minutes and reperfused for 60 minutes. Saline or 20 µg/kg of Alprost...

This study proposes a multi-frequency response piecewise-linear piezoelectric vibration energy harvester (MFRPLP-VEH) by combining the linear resonance and nonlinear bandwidth broadening methods to improve working frequency environmental robustness of harvester. A theoretical model is established based on electromechanical coupling dynamic MFRPLP-VEH. The harvesting performance width efficiency...

A low resting heart rate (HR) would be of great benefit in cardiovascular diseases. Ivabradine-a novel selective inhibitor of hyperpolarization-activated cyclic nucleotide gated (HCN) channels- has emerged as a promising HR lowering drug. Its effects on the autonomic HR control are little known. This study assessed the effects of chronic treatment with ivabradine on the modulatory, reflex and t...

Fetal/neonatal exposure to the endocrine disruptor bisphenol A (BPA) has induced obesity and increased glucose intolerance. We hypothesized that chronic BPA exposure would worsen the obesity and glucose intolerance induced by a high fat diet (HFD). The drinking water of C57bl/6n dams was treated with vehicle (VEH) or BPA (25 ng/ml) from gestation day 11.5 to postnatal day 21. Another group was ...

Cyclosporin A (CsA)-induced renal vasoconstriction (RV) is attributed to an imbalance in vasoactive factors release. Dexamethasone (Dex) exerts a renal vasodilatory effect by a mechanism not yet characterized. This study evaluates whether the effect of Dex is mediated by NO and whether it prevents CsA-induced RV. Micropuncture studies were performed in six groups of uninephrectomized rats treat...

OBJECTIVES Estrogen deficit following menopause results in cognitive behaviors impairment. This study aimed to evaluate the effects of pomegranate seed extract (PGSE) on avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO) in ovariectomized (OVX) rats. MATERIALS AND METHODS Adult female Wistar rats were divided randomly into eight groups with 8 rats in each g...

Impairments in behavior and cognition are common in individuals diagnosed with fetal alcohol spectrum disorders (FASD). In this study, FASD model rats were intragastrically intubated with ethanol (5g/kg/day; 5E), sham-intubated (SI), or maintained as naïve controls (NC) over postnatal days (PD) 4-9. Ethanol exposure during this human third trimester-equivalent period induces persistent impairme...

PURPOSE Dopamine (DA), which does not cross the blood-brain barrier, has central and behavioral effects when administered via the nasal route. Neither the mechanisms of central action of intranasal dopamine (IN-DA), nor its mechanisms of diffusion and transport into the brain are well understood. We here examined whether IN-DA application influences dopamine transporter (DAT) binding in the dor...