This paper presents the results of an effort to optimize a conceptual design of a conical (wingedcone) single-stage-to-orbit launch vehicle. The vehicle employs a rocket-based combined-cycle (RBCC) engine capable of four different operating modes ejector, ramjet, scramjet, and rocket. The RBCC engine offers higher engine thrust-to-weight ratios than competing airbreathing engine cycles while ma...

Present off-highway vehicle market demands low cost and light weight component to meet the NVH, Durability and need of cost effective vehicle with fuel efficient. This in turn gives the rise to more effective use of materials for vehicle parts which can reduce the overall weight with enhanced utility of vehicle for various applications. This paper briefs about how topology optimization techniqu...

background: phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed and sesame. vitex agnus-castus, also called vitex, owns phytoestrogenic properties. studies have showed that phytoestrogens have different impacts on the gestation process and reproduction indices. the present study is aimed at investigating the...

Fuel Economy and gHg standards design series the author would like to thank his colleagues John german, anup Bandivadekar and Joe schultz for their guidance and constructive comments, as well as all icct internal and external reviewers of this paper. ExEcutivE Summary the current carbon dioxide (co 2) emission performance standards for new passenger cars in the European Union are based on vehic...

Objective: Pomegranate juice is inhibitor of CYP450 enzyme system such as CYP2C9 and CYP3A4. The objective of the present study was to determine the consequence of pomegranate fruit juice on the pharmacokinetics of oral hypoglycemic drug nateglinide in rats. Materials and Methods: This is a laboratory study to investigate drug-food interaction effects of Punica granatum fruit juice (3 ml) and ...

The neuropeptide orexin (hypocretin) increases energy expenditure partially through increasing spontaneous physical activity. The ability of exogenous orexin to alter body weight has never been established, however. We sought to determine whether orexin-A microinjected into the paraventricular nucleus of the hypothalamus (PVN) induced weight loss in rats. Chronic guide cannulae were implanted i...