Denervation (DNV) of rat diaphragm muscle (DIAm) decreases myosin heavy chain (MHC) content in fibers expressing MHC(2X) isoform but not in fibers expressing MHC(slow) and MHC(2A). Since MHC is the site of ATP hydrolysis during muscle contraction, we hypothesized that ATP consumption rate during maximum isometric activation (ATP(iso)) is reduced following unilateral DIAm DNV and that this effec...

β-Adrenergic receptor (β-AR) stimulation increases extracellular ubiquitin (UB) levels, and extracellular UB inhibits β-AR-stimulated apoptosis in adult cardiac myocytes. This study investigates the role of exogenous UB in chronic β-AR-stimulated myocardial remodeling. l-Isoproterenol (ISO; 400 μg·kg(-1)·h(-1)) was infused in mice in the presence or absence of UB (1 μg·g(-1)·h(-1)). Left ventri...

We assess ice loss and velocity changes between 1985 and 2014 of three tidewater and fiveland terminating glaciers in Godthåbsfjord (Nuup Kangerlua), Greenland. Glacier thinning accounted for 43.8 ± 0.2 km of ice loss, equivalent to 0.10 mm eustatic sea-level rise. An additional 3.5 ± 0.3 km was lost to the calving retreats of Kangiata Nunaata Sermia (KNS) and Narsap Sermia (NS), two tidewater ...

Poly(ADP-ribose) polymerase (PARP) inhibition has recently been identified as a novel approach to treatment of experimental peripheral diabetic neuropathy (PDN). However, long-term inhibition of PARP, an enzyme involved in DNA repair, can potentially result in premature aging, loss of genome stability, and other side effects. This study evaluated potential synergistic interactions between low d...

Mortality rates for prostate cancer are low in Asia but high in the West. One explanation is the high level of soy consumption in Asia. Soy isoflavones reduce prostate tumor growth in many, but not all, animal models. Elevated levels of serum prostate-specific antigen (PSA) are a marker of prostate tumor growth. Our objective was to determine whether 12-month soy isoflavone supplementation woul...

objective(s) several studies have reported improved response of exercised hearts to myocardial infarction (mi). this study was aimed to evaluate the preventive role of treadmill exercise and diosgenin on cardiac marker enzymes, thiobarbituric acid reactive substances (tbars), total antioxidant status (tas), lipids, and electrocardiographic (ecg) patterns in isoproterenol (iso)-induced myocardia...

We study density-stable laminar miscible displacement flow of two iso-viscous Newtonian fluids in an inclined pipe (diameter D̂). We present a wide range of novel experimental results. We illustrate the non-monotone relation in displacement efficiency at the density difference moves from positive (density unstable) to negative (density stable), the efficiency being minimal for iso-dense fluids. ...

ISOBUS-Systeme sind Anwendungen der ISO 11783. Diese Norm regelt Kommunikation und Schnittstellen für die geräteübergreifende elektronische Verbindung, Steuerung und Bedienung von Komponenten in Traktoren und Arbeitsmaschinen. Der Beitrag gibt einen systematischen Überblick über die Funktionen des komplexen Normenwerks.