This vignette is written for R-usage. However, Anaquin is a framework covering the entire RNA-Seq workflow; reads alignment, transcriptome assembly, gene expression and differential analysis, etc. Consequently, the R-package (and it’s documentation) is a subset of the overall Anaquin framework. We also distribute a workflow guide with this vignette on how Anaquin can be integrated with a bioinf...

OBJECTIVE to identify staff and institutional factors associated with substandard care by midwives managing postpartum hemorrhage (PPH). METHODS A multicenter vignette-based study was e-mailed to a random sample of midwives at 145 French maternity units that belonged to 15 randomly selected perinatal networks. Midwives were asked to describe how they would manage two case-vignettes about PPH ...

A review of the literature revealed that control (or placebo) vignettes are not used in numerous studies in all areas that employ vignette-based methodology, which is a serious methodological and theoretical flaw. The nature of this flaw and its methodological and theoretical importance is outlined in this paper, as well as procedures and a model for developing control vignettes. Two studies on...

In this vignette we introduce the functionality of the qpgraph package to estimate eQTL networks from genetical genomics data. To meet the space and time constraints in building this vignette within the qpgraph package, we are going to simulate genetical genomics data instead of using a real data set. For this purpose, we will use the functionality described in another vignette from this packag...

BACKGROUND This experimental study in a population-based sample aimed to compare attitudes towards obesity following three different causal explanations for obesity (individual behavior, environmental factors, genetic factors). METHODS The data were derived from an online representative sample. A random subsample of n = 407 participants was included. Two independent variables were investigate...

We present a novel inspection framework to detect dirt and blemish in production line of optical fabrication automatically. To detect dirt defect from vignette surface, we use B-Spline to generate an ideal vignette surface and subtract the contaminated surface from the generated vignette surface to locate the defect. Besides, we apply some image processing methods to optimize our inspection fra...

BACKGROUND Vignettes are short stories about a hypothetical person, traditionally used within research (quantitative or qualitative) on sensitive topics in the developed world. Studies using vignettes in the developing world are emerging, but with no critical examination of their usefulness in such settings. We describe the development and application of vignettes to a qualitative investigation...

Vignette methodology can be a flexible and powerful way to examine individual differences in response to dangerous real-life scenarios. However, most studies underutilize the usefulness of such methodology by analyzing only one outcome, which limits the ability to track event-related changes (e.g., vacillation in risk perception). The current study was designed to illustrate the dynamic influen...