Maximal electroshock seizures (MES) in albino rats and pentylenetetarazole (PTZ) induced seizures in albino mice were used to study anticonvulsant activity of Vitex-negundo leaf extract. The ethanolic leaf extract of Vitex-negundo was administered orally in graded doses (250, 500 and 1000 mg/kg p.o) in both the experimental models and the effects were compared with diphenylhydantoin in MES meth...

ObjectiveAs the leaves of Vitex negundo L. possess anti-inflammatory and antioxidant properties, this study has been undertaken to evaluate the effect of Vitex negundo L. in experimentally induced inflammatory bowel disease (IBD) and to find its probable mechanism of action including its antioxidant potential. Methods-The extract of Vitex negundo L. was prepared by percolation method. Acute tox...

Vitex trifolia (Local name - Nirnocchi, sirunocchi) is well known for its medicinal property. The present investigation encompasses evaluation of antibacterial potential of Vitex trifolia against certain pathogenic bacterial strains. Preliminary phytochemical studies were also made and results are given.

Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of female reproductive conditions in Anglo-American and European practice. The objective of this systematic review was to evaluate the evidence for the efficacy and safety of Vitex extracts from randomised, controlled trials investigating women's health.Eight databases were searched us...

The scientific basis for the statement that plants and their active constituents play an important role in the prevention diseases is continuously advancing. In fact, the origin of many therapeutic substances from the genus Vitex. The genus Vitex contains 270 species distributed around the world. It is an interesting source of potential bioactive molecules, as iridoids compounds, flavonoids, di...

Effect of solvent residues of Vitex negundo L. and Cassia fistula L. leaves (0.5 and 1%) was studied on egg laying and adult emergence of Callosobruchus maculatus Fab. and on percentage of larval parasitism by Dinarmus vagabundus (Timberlake). Cowpea seeds treated with methanol and aqueous extract of Vitex, at these concentrations (0.5 and 1%), significantly reduced the number of eggs and emerg...

North Bangkok. ** Department of Chemistry, Faculty of Science, Ramkhamhaeng University. Abstract A new ecdysteroid, P5, has been isolated from the stem bark of aged trees (with flower) of vitex canescens. 20-Hydroxyecdysone, makisterone A, 24-epi-makisterone A, and canescensterone have also been isolated from both young trees (without flower) and aged trees (with flower) of vitex canescens. The...

Vitex leucoxylon is known to possess anti inflammatory activity. It was accidentally observed that local people of some regions use the leaves of vitex leucoxylon in jaundice and other liver ailments. There was no report of pharma-cological screening on liver. Hepatoprotective activity of the alcoholic extract of the leaves of vitex leucoxylon was found to be effective in protecting the liver f...

INTRODUCTION Increased bleeding is the most common cause of intrauterine device (IUD) removal. The use of alternative therapies to treat bleeding has increased due to the complications of medications. But most alternative therapies are not accepted by women. Therefore, conducting studies to find the right treatment with fewer complications and being acceptable is necessary. This study aimed to ...