K inetoplastid protozoa include the parasites Trypanosoma brucei, Trypanosoma cruzi, and various species of Leishmania that are responsible for African trypanosomiasis, Chagas’ disease, and leishmaniasis, devastating diseases that aff lict millions of victims largely in the tropical regions of the globe. In addition to eliciting long-standing interest from medical microbiologists, these intrigu...