BACKGROUND In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand how wall shear stress affects the structure and the function of endothelial cells, it is crucial to design and fabricate an in vitro multi-component parallel-plate flow chamber sy...

OBJECTIVE Low wall shear stress has been implicated in atherogenesis throughout the arterial tree, including the right coronary artery (RCA). The objective of this study was to determine the level of covariation of intimal thickness and wall shear stress in the human RCA. METHODS AND RESULTS Postmortem histological measurements of intimal thickness were compared with wall shear stresses calcu...

Background: The interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries.Objective: To understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT...

the steel shear wall and composite steel plate shear wall is introduced in recent three decade and is considered and is spread rapidly. composite steel plate shear wall which is made of a layer of thin steel sheet with coating of reinforced concrete in one or both sides of steel palate is considered a third generation of resistance shear walls against lateral loads that in addition to increasin...

The purpose of this study was to determine the influence of radial motion of an arterial wall on the shear stress that flowing blood imposes on the wall (wall shear stress). Wall shear stress is known to influence endothelial cell function and may play a role in atherogenesis, but its magnitude and distribution in the circulation are not well understood. To simulate arterial wall motion, we use...

the present research is concerned with the determination of ductility, over-strength and response modification factors of coupled steel shear wall frames. three structural models with various numbers of stories, bay width and coupling beam height were analyzed using static pushover and incremental nonlinear dynamic analyses. the ductility, over-strength and response modification factors for the...

OBJECTIVES It has been postulated that in the arterial system mean wall shear stress is maintained at a constant value. The present study was performed to investigate the level of wall shear stress in the common carotid artery (CCA) as function of age and possible interactions between diameter and storage capacity, defined as the absolute area change per heart beat, with mean wall shear stress....

This paper focuses on a hydraulic radius separation approach used to calculate the boundary shear stress in terms of bed and wall shear stress proposed in a trapezoidal channel. The average bed and sidewall shear stress in smooth trapezoidal open channels are derived after using Guo & Julien (2005) early equations taking a part of an investigation to cover both rectangular and trapezoidal chann...

The steel shear wall and composite steel plate shear wall is introduced in recent three decade and is considered and is spread rapidly. Composite steel plate shear wall which is made of a layer of thin steel sheet with coating of reinforced concrete in one or both sides of steel palate is considered a third generation of resistance shear walls against lateral loads that in addition to increasin...

The predilection of atherosclerotic lesions for specific sites in the arterial tree is believed to be related t o the wall shear stress, exerted by the blood flow. Measurement of the magnitude of the wall shear stress is difficult and is frequently determined by an extrapolation of the velocity field t o find the wall shear rate and an estimation of the viscosity of the fluid in the neighborhoo...