Background: Hepatic encephalopathy is defined as a neuropsychiatric brain dysfunction in acute or chronic liver failure. Infection and inflammation have crucial role in its pathophysiology. The purpose of our study was to demonstrate the relationship between toll-like receptor 4 (TLR4) expression and the encephalopathy induced with endotoxin in biliary cirrhotic rats. Methods: The present stud...

how to cite this article: malak m, barzgar m. baclofen induced encephalopathy in a 6-year-old boy with advanced renal failure. iran j child neurol. spring 2015;9(2):61-63.   abstract baclofen is a drug for many diseases for all ages, but it is hazardous in patients with renal failure. this article talks about a case of baclofen overdose in a child with renal failure. a 6-year-old boy admitted t...

a 33 yr old man, previously diagnosed with hypothyroidism, presented with decreased level of consciousness and generalized tonic-clonic (gtc) seizure to namazi hospital, shiraz, iran, during april 2015. the patient later referred with another episode of seizure like attack for which he received phenytoin, carbamazepine and levothyroxine and was discharged. during his last admission, the patient...

Background: Bilirubin encephalopathy is a clinical syndrome, associated with bilirubin toxicity in the central nervous system, resulting in chronic and permanent sequelae. It has been estimated that approximately 60% and 80% of term and preterm newborns develop jaundice in the first week of life, respectively. In the present study, we aimed to determine the prevalence, morbidity, and mortality ...

how to cite this article: tavasoli ar, rostami p, ashrafi mr, karimzadeh p. neurological and vascular manifestations of ethylmalonic encephalopathy. iran j child neurol. spring 2017; 11(2):57-60.   abstract objective ethylmalonic encephalopathy (ee) is a severe mitochondrial disease of early infancy clinically characterized by a combination of developmental delay, progressive pyramidal signs, a...

The cardinal symptom of acute encephalopathy is impairment consciousness onset during the course an infectious disease, with duration and severity meeting defined criteria. Acute consists multiple syndromes such as necrotizing encephalopathy, biphasic seizures late reduced diffusion clinically mild encephalitis/encephalopathy reversible splenial lesion. Among these syndromes, there are both sim...

BACKGROUND & AIMS It remains unknown what the prevalence of minimal hepatic encephalopathy is in Taiwan, a highly endemic country for chronic viral hepatitis infection. It is also unclear whether abnormal serum cytokine levels can be indicative of the presence of minimal hepatic encephalopathy. We aimed to standardize the tests of psychometric hepatic encephalopathy score and predictive value o...