The aim of this study was to evaluate the effect of ovarian tissue fragmentation before preservation at 4C in MEM on the morphology, apoptosis, and growth of ovine preantral follicles. After collection, the ovaries were divided into two halves, being one divided into two fragments (1/4 of the ovary). One fragment was subdivided into two fragments (1/8), being one fixed for histology (fresh cont...

BACKGROUND The aim of this study was to investigate follicular growth and steroid production in neonatal mouse ovary during in vitro culture. MATERIALS AND METHODS In this experimental study, 7-day-old mouse whole ovaries were cultured in α-MEM (medium supplemented with 100 mIU/ml recombinant follicle stimulating hormone, 1% insulin, transferrin and selenium (ITS), 5% fetal bovine serum (FBS)...

Background: Limited and fixed number of ovarian follicles undergo reducing changes from birth till menopause. In cancerous patients who exposed to sterilizing treatments such as chemotherapy, follicle decrease is faster and dominant. Main fertility preservation technique for these patients is ovarian cryopreservation and transplantation. Reanastomosis between recipient site and invader tissue i...

BACKGROUND Improved cancer therapeutics and enhanced cancer survivorship have emphasized the severe long-term side effects of chemotherapy. Specifically, studies have linked many chemotherapy agents with primary ovarian insufficiency, although an exact insult model has not yet been determined. To investigate and ultimately solve this problem, a novel device for extended study of mammalian ovari...

A 16 year old unmarried girl presented with complaints of abdominal distension, vomiting, constipation, difficulty in breathing and restlessness. On examination abdomen was grossly distended with fluid thrill. Ultrasonographic examination revealed that there was a huge cystic collection with internal debris, multiple septations involving the whole abdomen and pelvis originating from right ovary...

introduction: cyclosporine a (neoral) is one of the immunosuppresive drugs that because of wide distribution in whole body can cause many side effects in different organs this study was done because of this drug effect on rat,s ovary tissue. marerials and methods: in this study 45 rats divided in three equall groups. two groups named tested group and one group as witness group. test groups were...

a 22-year-old patient with 9 months of amenorrhea and a huge abdominal swelling was admitted to our institution with an ultrasonography report of a multiloculated cystic space-occupying lesion, almost taking up the whole abdomen (probably of ovarian origin), along with a single live intrauterine fetus. she delivered vaginally a boy baby within 4 hours of admission without any maternal complicat...