Boeck's sarcoid frequently produces widespread roentgenologic evidence of pulmonary disease without clinical signs or symptoms. Wright and Filley (1) reported normal pulmonary function studies in one such case. Others (2, 3, 4, 5) have reported a variety of effects of more advanced sarcoidosis on pulmonary function. This report is a study of pulmonary function in six cases of Boeck's sarcoid an...

Rabies is a widespread disease in African domestic dogs and certain wild canine populations. Canine rabies became established in Africa during the 20th century, coinciding with ecologic changes that favored its emergence in canids. I present a conceptual and terminologic framework for understanding rabies ecology in African canids. The framework is underpinned by 2 distinct concepts: maintenanc...

BACKGROUND Fibromyalgia is a syndrome characterized by the presence of widespread chronic pain. People with fibromyalgia report lower levels of Positive Affect and higher levels of Negative Affect than non-fibromyalgia peers. The Positive and Negative Affect Schedule (PANAS)-a widely used questionnaire to assess two core domains of affect; namely 'Positive Affect' and 'Negative Affect' -has a c...

Results: Mean scores were 3.96 4.3 for the MGC and 7.66 4.6 for the QMGS. Neither scale fit the Rasch model (Xp<0.05). The MGC had lower PSI (0.14) than the QMGS (0.7). There was evidence of local dependency in both scales, as well as DIF for ocular and generalized disease. Disordered thresholds were found in 6(60%) items of the MGC and in 4(31%) of the QMGS. Collapsing response options did not...

The N and W-Beijing families of Mycobacterium tuberculosis are phylogenetically closely related. The ability of the W-Beijing family to rapidly cause widespread disease is well described; however, few outbreaks involving the N family have been reported outside the New York City, N.Y., area. During 2002 to 2003, Seattle, Wash., experienced a rapidly expanding tuberculosis outbreak involving 38 p...

OBJECTIVE To provide data about wealth distribution in visceral leishmaniasis (VL)-affected communities compared to that of the general population of Bihar State, India. METHODS After extensive disease risk mapping, 16 clusters with high VL transmission were selected in Bihar. An exhaustive census of all households in the clusters was conducted and socio-economic household characteristics wer...

In the preceding papers of this series (1-4), experimental syphilis in the rabbit has been presented from the standpoint of the phenomena of the infection which develops about the site of t h e inoculation. Ordinarily, these are the only manifestations of infection which are observed in the rabbit, b u t u n d e r certain circumstances, a generalized disease m a y be produced which is analogous...