The power of multiple testing procedures can be increased by using weighted p-values (Genovese, Roeder and Wasserman 2005). We derive the optimal weights and we show that the power is remarkably robust to misspecification of these weights. We consider two methods for choosing weights in practice. The first, external weighting, is based on prior information. The second, estimated weighting, uses...

Heeter and Winn explore the concept of meaningful play, describe highlights of the Meaningful Play: Designing and studying games that matter conference, and introduce the articles in this issue.

as part of the moral order on the one hand and as pathological phenomena on the other. Dr. Riese writes interestingly of his seventeenth century theorists, and the reader will find much of what he has to say rewarding, especially with respect to the work of medical men so little known as de la Forge and de la Chambre. Rather than praise the obvious merits of Dr. Riese's monograph, however, I sh...

between sound and meaning within vast possible variations in the items under comparison, reducing the possibility of chance similarity. In contrast, there is a 'poverty of choice' of some other language features. " For example there are only six permutations for the ordering of the subject, object and verb that a language can use. Accordingly, there is a one in six chance that any two languages...

habitats directives. It is the fi rst such report to include EU-wide data on bird populations and the second one on habitat quality. While just over half of European bird species are listed as “secure”, the report fi nds that one in three European bird species is now threatened, including formerly common species such as the skylark and the turtle dove, whose populations shrank by 50 and 80%, re...

of crime ! He fell by the hand of a friend and boon companion. Six months after, on the 27th of May, 1856, providentially for the ends of justice and the interests of society, the perpetrator of this foul murder was convicted and sentenced to execution; and, on the 14th of last month, he, in the presence of 50,000 persons, suffered an ignominious death upon the scaffold. We might well leave him...