The two species of Withania i.e. Withania obtusifolia and Withania somnifera were usually misinterpreted because of their coexistence in mixed populations. The present investigation involves analyzed of interspecific relationship between these two species. A careful morphological, anatomic and phytochemical, identification of the two species has led to the findings that there was a slight varia...

Withania somnifera (L) Dunal is a well known Indian medicinal plant widely used in the treatment of many clinical conditions in India. It is an important drug commonly known as Asgand which has been used either single or in combination with other drugs in Unani as well as Ayurvedic system of medicine for centuries. It has been described by Dioscorides (78 AD) in his book “Kitab-ul-Hashaish”. As...

Withanolide A is an important secondary metabolite in Withania somnifera, which is having a high medicinal value and possesses potent anti-tumor and antioxidant properties. Distribution of withanolide A in various organs of Withania somnifera was investigated by High Performance Liquid Chromatography (HPLC) method. The quantitative distribution of withanolide A was different in various organs t...

Withania somnifera (L.) Dunal is an important ayurvedic medicinal plant known mainly for its rejuvenating properties. In vitro micropropagation or multiplication of Withania somnifera through apical shoot proliferation by using different concentrations of growth regulators in short period. Shoots were induced from the apical meristem of Withania somnifera on Murashige and Skoog (MS) basal media...

Withania somnifera, popularly known as Ashwagandha is widely considered to be an integral part of Ayurvedic and Indigenous medical systems for over centuries for the treatment of various ailments. Withanolides (steroid lactone), are the major active constituents present in the roots and leaves of Withania somnifera. In the present study, withaferin A (active component of Withania somnifera), a ...

OBJECTIVE The main objective of the current study was to observe the ameliorative effect of Withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology. MATERIALS AND METHODS In the present study, arsenic in the form of sodium arsenite was administered orally ...

Withania Somnifera Dunal know as Ashwagandha belong Solanaceae family. It is extensively used in most of the Indian herbal pharmaceuticals and nutraceuticals. The current study, evaluate in vitro cytotoxicity in 50% ethanol extract of root, stem and leaves of Withania Somnifera against five human cancer cell lines of four different tissues i.e. PC-3, DU-145 (prostrate), HCT-15 (colon), A-549 (l...

Withania somnifera (L.) Dun. (Solanaceae), known as Indian ginseng, is one of the most popular medicinal plants in India. Considering the importance and common use of this plant, it is necessary to investigate its holistic metabolite profile. However, with existing analytical methods which are based on TLC and HPLC‑UV (or MS), it is difficult to obtain information of the whole range of compound...

Objective: The main objective of the current study was to observe the ameliorative effect of Withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology. Materials and Methods: In the present study, arsenic in the form of sodium arsenite was administered orally ...

Antioxidants are the essential defense mechanism to protect the body against free radical damage. The objective of the study was to investigate the in vitro antioxidant activity of different parts of Withania somnifera (leaves, fresh tubers and dry tubers) towards free radical DPPH and the extent of inhibition of lipid peroxidation using hydrogen peroxide as prooxidant. The plant extracts exhib...