نتایج جستجو برای: wrap53
تعداد نتایج: 72 فیلتر نتایج به سال:
Small nuclear ribonucleoproteins (snRNPs), which are required for pre-mRNA splicing, contain extensively modified snRNA. Small Cajal body-specific ribonucleoproteins (scaRNPs) mediate these modifications. It is unknown how the box C/D class of scaRNPs localizes to Cajal Bodies (CBs). The processing of box C/D scaRNA is also unclear. Here, we explore the processing of box C/D scaRNA 2 and 9 by c...
Telomerase is a ribonucleoprotein comprising telomerase RNA and associated proteins. The formation of the telomerase holoenzyme takes place in the Cajal body (CB), a subnuclear domain that participates in the formation of ribonucleoproteins. CBs also contribute to the delivery of telomerase to telomeres. The protein WRAP53 is enriched within the CB and is instrumental for the targeting of telom...
Background: TP53 and the oncogene WRAP53 are adjoining genes, producing p53-WRAP53α sense-antisense RNA couples. WRAP53α is indispensable for p53 mRNA regulation and p53 induction following DNA damage. Up-regulated WRAP53β can induce neoplastic transformation and cancer cell survival. All these, along with the associations of WRAP53 single nu...
The incidence of colorectal cancer (CRC) in young patients (≤ 50 years of age) appears to be increasing. However, their clinicopathological characteristics and survival are controversial. Likewise, the biomarkers are unclear. We used the West China (2008-2013, China), Surveillance, Epidemiology, and End Results program (1973-2011, United States) and Linköping Cancer (1972-2009, Sweden) database...
AMA Abdelmoety A, Elhassafy M, Omar Said R, Elsheaita Mahmoud M. The role of UCA1 and WRAP53 in diagnosis hepatocellular carcinoma: A single-center case-control study. Clinical Experimental Hepatology - Manuscripts Accepted. 2023. doi:10.5114/ceh.2023.127569. APA Abdelmoety, A., Elhassafy, M., Said, R., Elsheaita, & Mahmoud, (2023). https://doi.org/10.5114/ceh.2023.127569 Chicago Amr Aly, Moham...
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