Mammalian Nedd4 and its budding yeast orthologue Rsp5 are members of a large family of HECT-domain-containing ubiquitin ligases. Besides possessing a Ca(2+)/lipid-binding domain, both ligases have multiple protein-interacting modules termed WW domains. The C-terminal WW domains mediate interactions with substrates, but the function of the first WW domain remains unclear. We found that expressio...

A 2-year tillage-based winter wheat (Triticum aestivum L.)-summer fallow (WW-SF) rotation has been practiced by the vast majority of farmers in the low-precipitation (<300 mm annual) rainfed cropping region of east-central Washington and north-central Oregon for 140 years. Until recently, alternative crops (i.e., those other than WW) so far tested have not been as economically viable or stable ...

An algorithm for the calculation of the hyper-Wiener index (WW) of benzenoid hydrocarbons (both cata- and pericondensed) is described, based on the consideration of pairs of elementary cuts of the corresponding benzenoid graph B. A pair of elementary cuts partitions the vertices of B into four classes. WW is expressed as a sum of terms of the form n11n22 + n12n21, each associated with a pair of...

We aimed to identify quantitative trait loci (QTL) for secondary traits related to grain yield (GY) in two BC1F2:3 backcross populations (LPSpop and DTPpop) under well-watered (4 environments; WW) and drought stressed (6; DS) conditions to facilitate breeding efforts towards drought tolerant maize. GY reached 5.6 and 5.8 t/ha under WW in the LPSpop and the DTPpop, respectively. Under DS, grain ...

Nedd4 is a member of a growing family of ubiquitin-protein ligases which consist of a lipid-binding domain, two to four WW domains and a C-terminal ubiquitin-protein ligase domain. The Nedd4 mRNA levels are developmentally regulated and Nedd4 protein is highly expressed in many mouse embryonic tissues. In this study we have used a far-Western screen to identify embryonic proteins that interact ...

YAP is a WW domain-containing effector of the Hippo tumor suppressor pathway, and the object of heightened interest as a potent oncogene and stemness factor. YAP has two major isoforms that differ in the number of WW domains they harbor. Elucidating the degree of co-operation between these WW domains is important for a full understanding of the molecular function of YAP. We present here a detai...

Cattle behavior, including measures of docility, is important to beef cattle producers not only from a human safety perspective but also due to potential correlations to economically relevant traits. Field data from the American Hereford Association was used to estimate genetic parameters for chute score (CS; = 25,037), weaning weight (WW; = 24,908), yearling weight (YW; = 23,978), and intramus...

Wp(IRn)Wp(IRn) uzayı ve bu uzaya ait bazı özellikler Krogstad [1] tarafından ispat edilmiştir. Bu çalışmada, tanımlanan uzayın p=1p=1 için özel durumu olan W(IRn)W(IRn) ele alındı. ww, IRIR reel sayılar kümesinde Beurling-Domar koşullarını sağlayan ağırlık fonksiyonu olmak üzere bir Ww(IR)Ww(IR) uzay üzerinde ∥.∥w‖.‖w normu tanımlandı. uzayının, normuna göre Banach olduğu ispatlandı. (Ww(IR),∥....