Both paclitaxel and docetaxel are mitotic inhibitors with similar mechanisms of action. In our patient, CME was thought to be secondary to paclitaxel use. Paclitaxel treatment was discontinued and capecitabine (Xeloda; Hoffman-LaRoche Inc, Nutley, NJ) was prescribed by the patient’s oncologist. Six weeks after cessation of paclitaxel treatment, the patient’s bestcorrected visual acuity improved...

background and objectives: to compare pathologic complete response (pcr) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (nact) by 5-fu or xeloda (capecitabine) with and without eloxatin (oxaloplatin injection). materials and methods: seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. two basic chemotherapy regi...

Background Metastatic Cholangiocarcinoma is a disease with a dismal prognosis. Treatment options are few, survival short and the side effects of treatments are burdensome. Metronomic chemotherapy can offer tumour regression and palliation. In this study we explore the responses of three patients to this treatment method in cases where conventional chemotherapy treatment has failed. Methods Thre...

Capecitabine (Xeloda) was developed as a pro-drug of fluorouracil (FU), with the aim of improving tolerability and intratumor drug concentrations through its tumorspecific conversion to the active drug. The purpose of this paper is to review the available information on capecitabine, focusing on its clinical effectiveness against various carcinomas. Identification of all eligible English trails...

1 = number of abstract – I’ll ask to have CRP added to my monthly bloodtest 2 – I’ll ask to have LDH added to my monthly bloodtest 3 and 4 – Taxotere (docetaxel) + estramustine (3x280 mg/day) better than Taxotere alone 5 – same as 3 and 4, but 3x140 mg/day estramustine equally effective as 3x280 mg, and less toxic 6 – Thalidomide + bevacizumab (Avastin) + Taxotere: works! 7 – Taxotere + Carbopl...

INTRODUCTION We report a case of stage IV breast cancer terminating in an unusual picture of radiologically occult micronodular pseudo-cirrhosis. Contrast-enhanced computed tomography showed no evidence of metastatic breast cancer within the liver. Unlike the few previously reported cases of intrasinusoidal spread of breast cancer, our patient was palliated with a transjugular intrahepatic port...