background: in this study, the toxicity of the different xenobiotics was tested on the fruit fly drosophila melanogaster model system.  methods: fly larvae were raised on food supplemented with xenobioticsat different concentrations (sodium nitroprusside (0.1-1.5 mm), s-nitrosoglutathione (0.5-4 mm), and potassium ferrocyanide (1 mm)). emergence of flies, food intake by larvae, and pupation hei...

Globally, the rapid rise in human population has increased crop production, resulting pesticide xenobiotics. Despite fact that xenobiotics toxify soil environment and ecosystem, synthetic pesticides have agricultural yields reduced disease vectors. Pesticide use increased, an increase environmental pollution. Various methods of controlling eliminating these contaminants been proposed to address...

The article summarizes and analyzes the main impacts of various xenobiotics or their groups on human body consequences such exposure. study suggests refinements to generally accepted classification xenobiotics’ origins. paper also describes molecular mechanism foreign substances biotransformation in a body. metabolism differs due forms types’ varieties. factors influence chemicals’ are great im...

Introduction The term xenobiotic (Greek xenos + bioticos, which means “strange” and “life-related” respectively) means a chemical substance that is not a natural component of a living organism exposed to it, i.e. a strange, exogenous substance or anthropogenic material. This definition covers substances strange to the target organisms, hence its use for most poisons and drugs. An important grou...

Co-oxidation of xenobiotics has been shown t o occur during prostaglandin synthase (PGS)-catalysed synthesis of prostaglandins (Marnett. 198 I ; EIing et al.. 1983; Marnett & Eling. 1983). PGS catalyses the oxygenation of polyunsaturated fatty acids to hydroxy endoperoxides (e.g. PGH2). The most important substrate in vivo is arachidonic acid (AA) . PGS contains two activities: the fatty acid c...